Publications by authors named "Squizzato F"

This report details the case of an 84-year-old male with an infrarenal abdominal aortic aneurysm and a dilated right common iliac artery eligible for endovascular treatment. A bifurcated stent graft (Medtronic Endurant IIs) was used to treat the aneurysm. To address the concerns of instability of the right iliac limb, four endoanchors (Heli-FX EndoAnchor, Medtronic) were placed at the distal landing zone to provide additional fixation.

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Background: Superior vena cava syndrome (SVCs) is a common complication in hemodialysis patients due to central vein occlusions, often caused by prior catheterizations. Management can be challenging.

Objective: To describe a successful endovascular approach to managing SVCs caused by right innominate vein (RIV) occlusion in a hemodialysis patient with a non-functional LeVeen shunt.

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  • * This text discusses the effectiveness of using carbon-dioxide (CO) instead of iodinated contrast for enhancing CBCT imaging during these interventions.
  • * The study found that CO-CBCT posed no adverse effects and delivered good imaging quality for assessing endograft integrity and vessel patency, especially in patients with serious kidney issues.
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Background: Intravenous thrombolysis (IVT) is the mainstay of treatment for patients presenting with acute ischemic stroke, whereas carotid endarterectomy (CEA) is indicated in patients with symptomatic carotid stenosis. However, the impact of prior IVT on the outcomes of CEA (IVT-CEA) is not clear. The aim of this study was to determine whether IVT may create additional stroke and death risk for CEA, compared with CEA performed in the absence of a history of recent IVT, and to determine the optimal timing for CEA after IVT.

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  • The study analyzed readmission rates and costs for patients with aorto-iliac occlusive disease (AIOD) who underwent either aorto-bifemoral bypass (ABF) or covered kissing stent (CKS) procedures from May 2008 to February 2018.
  • It found that readmission rates were similar for both procedures (ABF at 16%, CKS at 18%), with the primary cause being prosthesis limb or stent occlusion.
  • Although the CKS group showed a trend toward higher readmission and treatment costs, the ABF group experienced a longer time before readmission (35 months compared to 13.5 months for CKS).
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  • The study evaluates the use of the Excluder iliac branch endoprosthesis as an alternative to standard endovascular aortic repair for patients with specific conditions.
  • It was applied successfully in 13 cases involving abdominal/iliac aneurysms, occlusive disease, or complex aneurysms, achieving 100% technical success without adverse events.
  • At a follow-up of three months, all grafts demonstrated stability, highlighting the procedure's feasibility and safety in carefully selected cases.
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Objective: The aim of this study was to report the outcomes of endovascular urgent thoracoabdominal aortic (TAAA) repair, using an off-the-shelf preloaded inner branch device (E-nside; Artivion).

Methods: Data from a physician-initiated national multicenter registry, including patients treated with E-nside endograft (INBREED) were prospectively collected (2020-2024); only urgent cases were included in this study. Primary outcomes were technical success and mortality at 30 days.

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  • - The study evaluates a standardized method for using a specific type of endograft (four-fenestrated PMEG) to treat complex abdominal aortic aneurysms safely and effectively, focusing on specific anatomical criteria and techniques.
  • - Six patients (with various types of aneurysms) were treated, and the procedure was successful in all cases, with no complications or deaths reported within 30 days.
  • - Post-surgery imaging showed complete exclusion of the aneurysms without complications, indicating that this standardized approach may serve as a reference for future research.
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Objective: This study aimed to compare two commercially available off the shelf branched endografts for thoraco-abdominal aortic aneurysm (TAAA) repair, namely the E-nside (Artivion) and Zenith t-Branch (Cook Medical) devices.

Methods: This multicentre retrospective study (2020 - 2023) included patients treated by branched endovascular aortic repair (BEVAR) for TAAA using the inner branched E-nside or the outer branched t-Branch. Endpoints were 30 day technical success and major adverse events (MAEs) as well as one year freedom from target vessel instability and main endograft instability.

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  • This study aimed to assess how effective intravascular ultrasound (IVUS) is in evaluating and improving the placement of kissing stents (KSs) and covered endovascular reconstruction in treating severe aortoiliac obstructive disease.
  • Researchers conducted a retrospective review of 102 patients receiving endovascular treatments from 2019 to 2023, focusing on cases with specific conditions that warranted IVUS use during procedures.
  • The findings revealed that IVUS identified significant technical issues in 25% of patients, leading to successful corrective measures, with higher risks associated with severely calcified lesions and narrow aortic bifurcations among the patients.
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  • Carotid artery stenting (CAS) with new-generation Roadsaver dual-layer stents aims to improve outcomes compared to traditional stenting methods, which have worse results in plaque issues and cerebral embolization.
  • This study analyzed data from 353 patients who underwent CAS between 2017 and 2022 at three Italian centers, focusing on procedural success and adverse cerebrovascular events, including strokes and transient ischemic attacks.
  • Results showed a high technical success rate of 96.9%, with a low incidence of complications, indicating that the Roadsaver stent may offer better midterm safety and effectiveness for patients undergoing this procedure.
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The objective of these Guidelines is to provide recommendations for the classification, indication, treatment and management of patients suffering from aneurysmal pathology of the visceral and renal arteries. The methodology applied was the GRADE-SIGN version, and followed the instructions of the AGREE quality of reporting checklist. Clinical questions, structured according to the PICO (Population, Intervention, Comparator, Outcome) model, were formulated, and systematic literature reviews were carried out according to them.

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Carotid artery stenting (CAS) represents today an accepted option for the treatment of severe carotid artery stenosis. The evolution of materials, techniques, perioperative medical management and patients' selection, has allowed to progressively reduce CAS complications. However, the main drawback of CAS is still represented by the risk of cerebral embolization, that may occur during several steps of the procedure and also in the early postoperative period.

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Purpose: To describe the endovascular treatment of a symptomatic juxtarenal abdominal aortic aneurysm (JAAA) using a combination of endoanchors (Heli-FX EndoAnchor, Medtronic, Minneapolis, Minnesota) and a physician-modified single-fenestrated endograft.

Technique: An 85 year-old patient unfit for open aortic repair presented for a symptomatic JAAA, characterized by an infrarenal neck with 0.6 cm in length and 23 mm in diameter.

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Objective: This single centre, retrospective study (2014 - 2022) on juxta-, pararenal, or thoraco-abdominal aortic aneurysms treated by fenestrated endovascular aortic repair (FEVAR) was conducted to investigate the clinical impact and determinants of fenestration to target vessel misalignment in FEVAR.

Methods: Pre-operative supracoeliac, pararenal, and infrarenal aortic angles were measured on three dimensional computed tomography angiography (CTA) reconstructions. Two components of misalignment were measured on the first post-operative CTA: horizontal misalignment (angle between the fenestration and the target vessel ostium on perpendicular CTA cuts) and vertical misalignment (vertical distance between the fenestration and the target vessel at its origin).

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  • The study aimed to assess how a narrow paravisceral aorta (NPA) affects the stability of target vessels (TVI) after undergoing fenestrated-branched endovascular aortic repair for aortic aneurysms.
  • A total of 142 patients were analyzed, with 70% having NPA, and both groups displayed high rates of technical success and low mortality within 30 days.
  • The long-term freedom from TVI at 4 years was similar for patients with and without NPA, although having an NPA less than 20 mm and a significant angulation (>30°) was linked to a higher risk of TVI specifically in the FEVAR subgroup.
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Objective: The aim of this study was to investigate the outcomes of primary determinate and indeterminate target vessel endoleaks (TVELs) after fenestrated-branched endovascular aortic repair (F-BEVAR).

Methods: We conducted a single-center retrospective study (2014-2023) on F-BEVAR for thoracoabdominal (TAAAs) or pararenal aortic aneurysms (PRAAs). TVELs were classified as "primary" if present at the first postoperative computed tomography angiogram.

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Background: The carotid stent design may influence the risk of embolization during carotid artery stenting. The aim of the study was to assess this risk by comparing the quantity of embolized material captured by filters during carotid artery stenting, using different stent designs.

Methods: We conducted a single-center retrospective study of patients undergoing carotid artery stenting for asymptomatic carotid stenosis >70% (2010-2022) in a tertiary academic hospital (Padua University Hospital, Italy).

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We describe the feasibility of a technique for temporary aneurysm sac reperfusion after endovascular single-stage thoracoabdominal aortic aneurysm exclusion, to be used in the case of postoperative spinal cord ischemia. Two cases were treated for impending rupture of a thoracoabdominal aortic aneurysm. Before completion of sac exclusion, a supplementary buddy wire (V-18 control guidewire; Boston Scientific) was advanced in parallel fashion from the left percutaneous femoral access into the aneurysmal sac on the posterior aspect of the endograft.

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Multimodal imaging is the incorporation of two or more imaging modalities during the same examination, and it has both diagnostic and treatment applications. The use of image fusion for intraoperative guidance in endovascular interventions is being extended increasingly to the field of vascular surgery, especially in the context of hybrid operating rooms. The aim of this work was to perform a review and narrative synthesis of the available literature in order to report on current applications of multimodal imaging in diagnosis and treatment of emergent vascular conditions.

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  • The study evaluated the occurrence of acute kidney injury (AKI) stages post-fenestrated endovascular aortic repair (FEVAR) in patients with complex aortic aneurysms, using the RIFLE criteria to classify AKI severity.
  • It included 45 patients, primarily elderly males, and found a 11.1% incidence of post-operative injury stage AKI, while examining predictors of AKI and long-term renal function decline.
  • Key predictors of chronic kidney disease onset identified were older age and post-operative injury stage AKI, though some factors showed significance only in univariate analysis and not in multivariate models.
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Background: The aim of this work is to value cost-effectiveness of complex aortoiliac occlusive disease (AIOD) revascularization, by comparing in-hospital clinical outcomes and detailed costs of hospitalization of open and endovascular techniques.

Methods: This observational single-center retrospective cohort study included all patients who underwent AIOD revascularization from May 2008 to February 2018 and met inclusion and exclusion criteria. Patients were divided into 2 groups: open surgical repair and endovascular repair.

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