Classification of Events Violating the Safety of Physical Layers in Fiber-Optic Network Infrastructures.

Fiber-optic network infrastructures are crucial for the transmission of data over long and short distances. Fiber optics are also preferred for the infrastructure of in-building data communications. In this study, we use polarization analysis to ensure the security of the optical fiber/cables of the physical layer.

Physical Layer Components Security Risks in Optical Fiber Infrastructures.

Optical fiber communications are essential for all types of long- and short-distance transmissions. The aim of this paper is to analyze the previously presented security risks and, based on measurements, provide the risk level evaluation. The major risk is the possibility of inserting a splitter into the optical distribution network and capturing a portion of the entire spectrum, i.

Combination therapy of colorectal carcinoma.

The aim of the study was to optimise the present therapy for colorectal carcinoma according to the standard therapeutic protocol. At the Ist Department of Surgery of the LF MU St. Anna Hospital in Brno and at the Department of Radiation Oncology of the same hospital, 262 patients with colorectal carcinoma were treated in period 2000-2002.

[Cytoprotective effects of amifostine in the treatment of tumors].

An efficient therapy of patients with tumorous diseases should include maximum killing of malignant cells with minimal damage to cells in healthy tissues. Radiotherapy and chemotherapy are frequently associated with a series of undesirable effects. Side effects related to the therapy may unfavorably influence quality of life for a short or long period of time, may cause the need to decrease the dosage or shorten the overall period of treatment or survival of the patient.

Gemcitabine monotherapy in patients with locally advanced or metastatic pancreatic cancer: a prospective observational study.

Pancreatic cancer has one of the worst prognosis of any malignant disease. Systemic therapy is often administered because the disease is usually detected at advanced stages. Gemcitabine (Gemzar trade mark, Eli Lilly & Co.

Relation of prenephrectomy CD profiles and serum cytokines to the disease outcome and response to IFN-alpha/IL-2 therapy in renal cell carcinoma patients.

Immune parameters, including cytokine levels and CD profiles were determined in 78 renal cell carcinoma patients (RCC) prior to nephrectomy. The values were correlated with the outcome of disease and response to cytokine-based treatment during a 3-year follow-up. Significantly lower frequency of progressions and higher proportion of survivors were recorded in 24 treated patients compared to 43 untreated ones (22.

Renal cell carcinoma-associated immune impairment that may interfere with the response to cytokine therapy.

This prospective study was carried out to explore cytokine-related immune alterations in 69 renal cell carcinoma patients (RCC) and to look for changes which might potentially serve as a reliable predictors of response to cytokine-based therapy. Interleukin-2 (IL-2), its soluble receptor (sIL-2R) and tumor necrosis factor (TNF-alpha) levels produced in vitro by PHA activated and intact mononuclear cells (PBMC) were determined. Concentrations of IL-2, IL-4, IL-6, sIL-2R, TNF-alpha and CRP were measured in sera.

[Treatment of Graves' ophthalmopathy with irradiation].

Orbital radiation therapy appears to be an effective and safe treatment of Graves' ophthalmopathy. Five patients with Graves' ophtalmopathy were treated with external beam radiotherapy during 1996 and 1997 in St. Ann University Hospital.

[Basic principles of the treatment of metastasis of adenocarcinoma of long bones and pelvis.].

Authors evaluated longterm results of the survival of patients with metastasis of adenocarcinoma in long bones and pelvis in 72 cases which were treated and followed at Ist Orthpaedic Clinic of the Faculty Hospital of St. Ann in Brno in the period of 1970-1995. Patients were divided into two groups.

[Metal stents in patients with malignant and benign esophageal stenoses].

The authors used between October 1993 and January 1997 in 131 patients with inoperable malignant or benign stenosis of the oesophagus an expansible metal stent. In 25 patients the stenosis was in the upper third of the oesophagus, in 44 in the medium part, in 53 in the lower third of the oesophagus and in 9 patients in the area of the anastomosis. All patients suffered at the time when the stent was introduced from marked dysphagia (stage 3-4 according to the international classification).

Stage IIb, IIIb, and IVa carcinoma of the uterine cervix--results of treatment by radiotherapy in 649 patients.

During the period of January 1969 to December 1980, 649 patients have been treated by radical radiotherapy for Stage IIb, IIIb, and IVa carcinoma of the cervix uteri. This retrospective study was performed to assess therapeutical results in two groups of patients. Clinical staging and the methods of treatment were standard in both groups.

Carcinoma cervicis uteri. Long-term follow-up therapeutic results.

The principle of the therapy of carcinoma cervicis uteri in the Research Institute of Clinical and Experimental Oncology in Brno is the combination of betatron megavoltage irradiation and cobalt 60 irradiation with intracavital radium irradiation. On the basis of many years' study concerning the therapy and therapeutic results of this tumor accurate directions of total therapy were elaborated. Carcinoma is diagnosed and classified precisely according to valid international directions.

Study of radiation dose fractionation in some tumor types.

In the presented work we have tested another fractionation schemes than simple fractionation in some so-called radioresistant tumors, i. e. in breast cancer and malignant melanoma.

Possibilities of motion therapy using betatron.

Two modalities of motion therapy both with electron and bremsstrahlung irradiation are described. Both therapy modes were used in the therapy of 62 patients with tumors of the kidneys, 13 patients with tumors of the esophagus, 20 patients with tumors of the prostate and urinary bladder and 170 patients with tumors of the breast. The advantage of the described method is the possibility of simple, precise and easily reproducible irradiation in given localizations, good therapeutic effect and very good general tolerance as the patient concerns.

Use of 42 MeV betatron bremsstrahlung irradiation in the therapy combined with radium in carcinoma of the cervix.

The article deals with the therapy of cancer of the cervix with external 42 MeV betatron bremsstrahlung irradiation in combination with intracavitary applicated radium. The described irradiation technique using special shielding blocks extends the dose distribution till to the region of paraaortic nodes in an extended field. The extended irradiation field is used on the basis of lymphographic examination.