Effectiveness of the First and Second Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine Dose: A Nationwide Cohort Study From Austria on Hybrid Versus Natural Immunity.

Background: We aimed to evaluate the effectiveness of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccinations in previously SARS-CoV-2-infected adults in the general population of Austria during the Delta wave and with extended follow-up.

Methods: In a nationwide retrospective cohort study, we calculated age-, sex-, and nursing home residency-adjusted Cox proportional hazard ratios (HRs) of coronavirus disease 2019 (COVID-19) deaths, SARS-CoV-2 infections, and non-COVID-19 deaths from 1 October to 31 December 2021, and secondarily with extended follow-up to 30 June 2022. Relative vaccine effectiveness (rVE) is rVE = (1 - HR) × 100.

Using stable isotopes to inform water resource management in forested and agricultural ecosystems.

Present and future climatic trends are expected to markedly alter water fluxes and stores in the hydrologic cycle. In addition, water demand continues to grow due to increased human use and a growing population. Sustainably managing water resources requires a thorough understanding of water storage and flow in natural, agricultural, and urban ecosystems.

Small RNAs direct attack and defense mechanisms in a quorum sensing phage and its host.

Many, if not all, bacteria use quorum sensing (QS) to control collective behaviors, and more recently, QS has also been discovered in bacteriophages (phages). Phages can produce communication molecules of their own, or "listen in" on the host's communication processes, to switch between lytic and lysogenic modes of infection. Here, we study the interaction of Vibrio cholerae with the lysogenic phage VP882, which is activated by the QS molecule DPO.

Identifying key policy objectives for strong primary care: a cross-sectional study.

Aim: The aim of this study was to identify key policy objectives by investigating the perception of important stakeholders and affected professionals concerning relevance and feasibility of a successful primary care (PC) reform.

Background: Since 2013, the Austrian PC system has been undergoing a reform process to establish multiprofessional primary care units. The reforms have various defined objectives and lack clear priorities.

Challenges in studying water fluxes within the soil-plant-atmosphere continuum: A tracer-based perspective on pathways to progress.

Tracing and quantifying water fluxes in the hydrological cycle is crucial for understanding the current state of ecohydrological systems and their vulnerability to environmental change. Especially the interface between ecosystems and the atmosphere that is strongly mediated by plants is important to meaningfully describe ecohydrological system functioning. Many of the dynamic interactions generated by water fluxes between soil, plant and the atmosphere are not well understood, which is partly due to a lack of interdisciplinary research.

In Vivo Monitoring of Acute and Intermittent Fatigue in Sport Climbing Using Near-Infrared Spectroscopy Wearable Biosensors.

The objectification of acute fatigue (during isometric muscle contraction) and cumulative fatigue (due to multiple intermittent isometric muscle contractions) plays an important role in sport climbing. The data of 42 participants were used in the study. Climbing performance was operationalized using maximal climbing-specific holding time (CSHT) by performing dead hangs.

Offsetting environmental impacts beyond climate change: the Circular Ecosystem Compensation approach.

Since the Paris Agreement entered into force, climate neutrality and associated compensation schemes are even more on the agenda of politics and companies. Challenges of existing offsetting schemes include the rather theoretical saving scenario and the limited scope of considered impacts. To address some of these limitations, this paper proposes the Circular Ecosystem Compensation (CEC) approach based on monetization of LCA results and Ecosystem Valuation.

Evaluation of Influencing Factors on the Maximum Climbing Specific Holding Time: An Inferential Statistics and Machine Learning Approach.

Handgrip strength (HGS) appears to be an indicator of climbing performance. The transferability of HGS measurements obtained using a hand dynamometer and factors that influence the maximal climbing-specific holding time (CSHT) are largely unclear. Forty-eight healthy subjects (27 female, 21 male; age: 22.

The Performance-Result Gap in Mixed-Reality Cycling - Evidence From the Virtual Tour de France 2020 on Zwift.

Mixed-reality sports are increasingly reaching the highest level of sport, exemplified by the first Virtual Tour de France, held in 2020. In road races, power output data are only sporadically available, which is why the effect of power output on race results is largely unknown. However, in mixed-reality competitions, measuring and comparing the power output data of all participants is a fundamental prerequisite for evaluating the athlete's performance.

The fungivorous amoeba Protostelium aurantium targets redox homeostasis and cell wall integrity during intracellular killing of Candida parapsilosis.

Predatory interactions among microbes are major evolutionary driving forces for biodiversity. The fungivorous amoeba Protostelium aurantium has a wide fungal food spectrum including foremost pathogenic members of the genus Candida. Here we show that upon phagocytic ingestion by the amoeba, Candida parapsilosis is confronted with an oxidative burst and undergoes lysis within minutes of processing in acidified phagolysosomes.

Correlation of atherosclerosis and osteoarthritis in ancient Egypt: A standardized evaluation of 45 whole-body CT examinations.

Objective: To correlate atherosclerosis (Ath) and osteoarthritis (OA) in mummies from ancient Egypt.

Materials: Whole-body CT examinations of 23 mummies from the Ägyptisches Museum und Papyrussammlung, Berlin, Germany, and 22 mummies from the Museo Egizio, Turin, Italy.

Methods: Ath was assessed in five anatomical regions by means of preserved arterial calcifications.

Evaluating sedimentary PAH bioavailability based on equilibrium partitioning and passive sampling at the Dover Gas Light Superfund Site (Dover, Delaware, USA).

From 1859 to 1948, the Dover Gas Light plant produced combustible gas for industrial, commercial, and residential applications using pine resin, coking coal, oil, and wood, and finally, a coal-gas process. Waste coal tar was discharged into the St. Jones River in Dover, Delaware (USA), via a ditch and culvert and, following plant closure in the 1940s, through groundwater flow from structures buried on the site.

A TRP1-marker-based system for gene complementation, overexpression, reporter gene expression and gene modification in Candida glabrata.

Although less prevalent than its relative Candida albicans, the yeast Candida glabrata is a successful pathogen of humans, which causes life-threatening candidiasis. It is thus vital to understand the pathogenicity mechanisms and contributing genes in C. glabrata.

Effects of black carbon and mineral dust on glacial melting on the Muz Taw glacier, Central Asia.

Light-absorbing impurities (LAIs), including black carbon (BC) and mineral dust, in snow can trigger a positive feedback. In this study, we estimate the contribution of BC and dust to glacial melting in Central Asia. Average BC and dust concentrations in the surface snow of the Muz Taw glacier are 1788 ± 1754 ng g and 172 ± 178 μg g, respectively.

Data on DOC and N from the Muz taw glacier in Central Asia.

This Data in Brief article provides a supplementary information to the dissolved organic carbon and nitrogen from the snow of Muz taw glacier in the Central Asia, which is related to the scientific article titled with "Characterization, sources and transport of dissolved organic carbon and nitrogen from a glacier in the Central Asia"[1]. Meanwhile, major ions (including Na, , NH , Ca, Mg, Cl, SO , NO , and NO ) were also reported. These data were analysed using descriptive statistics such as correlations and principle component analysis.

Fungal biotin homeostasis is essential for immune evasion after macrophage phagocytosis and virulence.

Biotin is an important cofactor for multiple enzymes in central metabolic processes. While many bacteria and most fungi are able to synthesise biotin de novo, Candida spp. are auxotrophic for this vitamin and thus require efficient uptake systems to facilitate biotin acquisition during infection.

[Integrated Complex Treatment for Extreme Anorexia Nervosa; An Interdisciplinary Treatment Concept of the University Hospital Zurich].

Integrated Complex Treatment for Extreme Anorexia Nervosa; An Interdisciplinary Treatment Concept of the University Hospital Zurich The serious physical mental and psychosocial morbidity due to anorexia nervosa is often perceived by sufferers as less serious than from their environment. Doctors and other healthcare professionals are therefore confronted with the difficulty that urgent medical treatment is considered as unnecessary or even threatening by those affected. Although patients with anorexia nervosa usually wish to improve their condition, they are usually only able to tolerate treatment aimed at normalizing eating behavior and gaining weight in response to high external pressure.

Extraction and Visual Analysis of Potential Vorticity Banners around the Alps.

Potential vorticity is among the most important scalar quantities in atmospheric dynamics. For instance, potential vorticity plays a key role in particularly strong wind peaks in extratropical cyclones and it is able to explain the occurrence of frontal rain bands. Potential vorticity combines the key quantities of atmospheric dynamics, namely rotation and stratification.

Health concepts of elementary school pupils in Austria : An explorative study using the draw and write technique.

Studies analysing health concepts of children are scarce. Thus, the aim of this study was to analyse health concepts of elementary school children in Austria. In all, 240 pupils in grades 2 (7 or 8 years old) and 4 (9 or 10 years old) of three rural and three urban elementary schools in Styria took part in this explorative study.

RNAi as a Tool to Study Virulence in the Pathogenic Yeast .

The yeast is a major opportunistic pathogen causing mucosal and systemic infections in humans. Systemic infections caused by this yeast have high mortality rates and are difficult to treat due to this yeast's intrinsic and frequently adapting antifungal resistance. To understand and treat infections, it is essential to investigate the molecular basis of virulence and resistance.

How to improve antibiotic awareness campaigns: findings of a WHO global survey.

Introduction: We aimed to examine the characteristics of antibiotic awareness campaigns (AAC) conducted on a national or regional level since 2010.

Methods: In October 2016, the WHO invited stakeholders involved in the planning or conduct of AACs to answer a web questionnaire. We solicited general information about the characteristics of the AAC, with a particular focus on key messages supporting optimal use of antibiotics.

Marine versus Continental Sources of Iodine and Selenium in Rainfall at Two European High-Altitude Locations.

The essential elements selenium (Se) and iodine (I) are often present in low levels in terrestrial diets, leading to potential deficiencies. Marine I and Se emissions and subsequent atmospheric wet deposition has been suggested to be an important source of I and Se to soils and terrestrial food chains. However, the contribution of recycled moisture of continental origin to I and Se to precipitation has never been analyzed.

Survival in early lung cancer patients treated with high dose radiotherapy is independent of pathological confirmation.

Background: Approximately 15% of lung cancer patients are diagnosed in early stages. Microscopic proof of disease cannot always be obtained because of comorbidity or reluctance to undergo invasive diagnostic procedures. In the current study, survival data of patients with and without pathology are compared.