Neovascularisation in flexor carpi ulnaris tendinopathy: novel combined sclerosing therapy and eccentric training of the forearms in athletics' wrist pain.

Tendinopathy of the flexor carpi ulnaris tendon is a rare entity. We present a 35-year old tennis player suffering tremendous pain (visual analogue scale (VAS) rating of 9/10) at the flexor carpi ulnaris tendon with adjacent calcification in close proximity to the pisiform bone. Sclerosing therapy using polidocanol under power and laser Doppler guidance was initiated, with immediate decrease of capillary blood flow by 25% with resolution of the neovascularisation in power Doppler.

Human Rad52-mediated homology search and annealing occurs by continuous interactions between overlapping nucleoprotein complexes.

The Rad52 protein has critical functions in distinct pathways of the homology-directed DNA repair, one of which is to promote the annealing of complementary strands of DNA. Both yeast and human Rad52 proteins organize into ring-shaped oligomers with the predominant form being a heptamer. Despite the wealth of information obtained in previous investigations, how Rad52 mediates homology search and annealing remains unclear.

Ferroplasma acidarmanus RPA2 facilitates efficient unwinding of forked DNA substrates by monomers of FacXPD helicase.

The strand-separation activity that is important for many cellular DNA processing machineries is provided by DNA helicases. In order to understand the physiological properties of a helicase acting in the context of its macromolecular machinery, it is imperative to identify the proteins that interact with the enzyme and to analyze how these proteins affect its helicase activities. The archaeal Rad3 helicase XPD (xeroderma pigmentosum group D protein) from Ferroplasma acidarmanus (FacXPD) is a superfamily II 5'-->3' DNA helicase.

Midportion achilles tendon microcirculation after intermittent combined cryotherapy and compression compared with cryotherapy alone: a randomized trial.

Background: The effect of combined cryotherapy/compression versus cryotherapy alone on the Achilles tendon is undetermined.

Hypothesis: Standardized combined cryotherapy/compression changes in midportion Achilles tendon microcirculation are superior to those with cryotherapy during intermittent application.

Study Design: Controlled laboratory study.

Engineering of functional replication protein a homologs based on insights into the evolution of oligonucleotide/oligosaccharide-binding folds.

The bacterial single-stranded DNA-binding protein (SSB) and the archaeal/eukaryotic functional homolog, replication protein A (RPA), are essential for most aspects of DNA metabolism. Structural analyses of the architecture of SSB and RPA suggest that they are composed of different combinations of a module called the oligonucleotide/oligosaccharide-binding (OB) fold. Members of the domains Bacteria and Eukarya, in general, contain one type of SSB or RPA.

Neovascularisation in de Quervain's disease of the wrist: novel combined therapy using sclerosing therapy with polidocanol and eccentric training of the forearms and wrists-a pilot report.

De Quervain's disease has been described as an entrapment of the extensor pollicis brevis and abductor pollicis tendons in the first dorsal compartment of the wrist is a common cause of wrist and hand pain. Currently, intrasheath corticosteroid injections have been reported to be successful as well as surgical release of the first dorsal compartment. We report on three female recreational athletes (median age 57 years, pain VAS 7/10) where we found significant neovascularisation of the extensor retinaculum using Power-Doppler sonography, which was not evident among subjects without de Quervain's disease of the wrist.

No change of palmar microcirculation at rest 2 years after radial artery harvesting.

Background: Radial artery forearm flaps are used for reconstruction of soft tissue defects. However, the functional consequences of removal of the radial artery for hand perfusion remain unclear at rest. We hypothesised that baseline microcirculation at rest is different following removal of the radial artery in a long-term perspective.

[Delayed DMCA-flap in a case of infection in the finger].

Introduction: After its first description 1990 by Maruyama, the DMCA flap has been used for several indications. In 1999 Pelissier published his "extended DMCA flap" with a wider arc of rotation. Compared to the most frequent indications for the DMCA flap, palmar digital soft tissue defects after infection are rare.

Lower limb revascularisation preceding surgical wound coverage - an interdisciplinary algorithm for chronic wound closure.

Background: Chronic wounds may occur or persist due to arterial insufficiency. Despite the high prevalence of arterial occlusive disease, a search of the literature has yielded a paucity of data on the benefit of interventions to recanalise lower extremity arteries prior to surgical closure of chronic wounds.

Objective: To investigate the correlation of simple clinical examinations and apparative diagnostics for the detection of arterial occlusive disease of the lower extremity in patients with chronic wounds, and to evaluate the benefit of vascular procedures to optimise wound perfusion before surgical closure.

Efficient absorbing boundary conditions for Biot's equations in time-harmonic finite element applications.

Absorbing boundary conditions for two phase media previously presented by Zerfa and Loret [Earthquake Eng. Struct. Dyn.

[Nerve and muscle transfer surgery to restore paralyzed elbow function].

Paralysis of elbow flexion or extension leads to major impairment of upper extremity function. Surgical reconstruction can be achieved using several procedures. If the time interval since the nerve injury is short, anatomic reconstruction by means of nerve suture or nerve transplantation should be attempted.

Outcome of simultaneous and staged microvascular free tissue transfer connected to arteriovenous loops in areas lacking recipient vessels.

Background: Arteriovenous loops are an indispensable tool in free flap surgery when appropriate recipient vessels are missing. In this study, the authors analyzed whether the outcome differs when flaps were transferred simultaneously or subsequently after construction of arteriovenous loops.

Methods: Twenty-seven patients requiring free tissue transfer received arteriovenous loops by pedicled or free vein grafts because of inadequate local recipient vessels.