Primary transpupillary thermotherapy for choroidal melanoma in 391 cases: importance of risk factors in tumor control.

Purpose: To report the long-term outcome of primary transpupillary thermotherapy (TTT) for choroidal melanoma.

Design: Retrospective review of medical records.

Participants: We included 391 patients with choroidal melanoma treated between 1995 and 2012 at the Oncology Service, Wills Eye Hospital, Philadelphia.

Iris metastasis from systemic cancer in 104 patients: the 2014 Jerry A. Shields Lecture.

Purpose: To describe the clinical features, treatment, and outcome of patients with iris metastasis.

Methods: Retrospective case series of 160 tumors in 107 eyes of 104 patients with iris metastasis from systemic cancer.

Results: The median age at presentation with iris metastasis was 60 years.

American joint committee on cancer staging of uveal melanoma.

In January 2010, the American Joint Committee on Cancer (AJCC) updated its staging criteria for uveal melanoma. Here, we discuss the staging classifications and evaluate an interesting case to demonstrate. The development of a uniform means of staging cancer, such as defined by the AJCC, is critical for information sharing among the research community.