Publications by authors named "Spencer Laehn"

BackgroundMechanically ventilated COVID-19 acute respiratory distress syndrome (ARDS) patients often receive deeper sedation and analgesia to maintain respiratory compliance and minimize staff exposure, which incurs greater risk of iatrogenic withdrawal syndrome (IWS) and has been associated with worse patient outcomes. To identify potential risk factors and differences in patient outcomes associated with the development of IWS in COVID-19 ARDS patients. Retrospective analysis of ventilated COVID-19 ARDS intensive care unit (ICU) patients who received continuous intravenous (IV) analgesia and sedation for ≥5 days from March 2020-May 2021.

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Background: To evaluate the impact of postoperative depth of sedation in free flap transfers to the head and neck.

Methods: A single center, retrospective cohort of 92 patients were stratified by depth of sedation, light sedation (RASS -1 or greater) or deep sedation (RASS less than -1), and analyzed for postoperative flap and medical complications.

Results: Of the 92 patients 45 were included in the light sedation and 47 in the deep sedation group.

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Purpose: The aim of the study was to summarize the evidence of the validation of CKD-EPI equation and alternative creatinine-based equations in Asian population.

Methods: Relevant validation studies of CKD-EPI and other creatinine-based equations were identified by a systematic literature searching of PubMed conducted from January 2009 through August 2014. Searching terms included "CKD EPI", "Kidney function test [MeSH] and validation", and "Glomerular filtration rate [MeSH] and validation" without language or design of study restrictions.

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