Publications by authors named "Spencer J Poiset"
Purpose: Glioblastoma (GBM) is the most common primary brain cancer in adults with a very poor prognosis. Metabolic drivers of tumorigenesis are highly relevant within the central nervous system, where glucose is the critical source of energy. The impact of obesity on survival outcomes in patients with GBM is not well established.
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- Local treatment options for recurrence of pancreatic adenocarcinoma are limited, with median survival times of 9-13 months, but MRI-guided stereotactic body radiation therapy (MRgSBRT) may improve outcomes by allowing higher radiation doses while protecting normal tissue.
- In a study involving 15 patients treated with MRgSBRT, the median overall survival after recurrence was 14.1 months, with local control rates of 92.3% and 83.9% at 6 and 12 months, respectively.
- The treatment showed manageable side effects, with 47% experiencing mild acute gastrointestinal toxicity and 31% facing chronic gastrointestinal issues, but no severe
Objective: Treatment of craniopharyngioma typically entails gross total resection (GTR) or subtotal resection with adjuvant radiation (STR-RT). We analyzed outcomes in adults with craniopharyngioma undergoing GTR versus STR-RT.
Methods: This retrospective study enrolled 115 patients with craniopharyngioma in 5 institutions.
Background: Hemangioblastoma of the central nervous system is an uncommon benign neoplasm, with about 25% of cases in patients with von Hippel-Lindau disease. The incidence of metastasis is rare, particularly in patients without von Hippel-Lindau disease. We report a case of hemangioblastoma with leptomeningeal dissemination as a late recurrence.
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