Outcomes of Omniflow® II prosthesis used for revascularization in the femoral tract both in infected and non-infected setting.

Background: Evidence regarding the outcomes of Omniflow II prosthesis in peripheral arterial revascularization at different anatomical sites and for different indications is scarce. Therefore, the aim of this study was to evaluate the outcomes of the Omniflow II used at various positions within the femoral tract both in infected and non-infected setting.

Methods: Patients who underwent reconstructive lower leg vascular surgery with implantation of an Omniflow II from 2014 until 2021 at five medical centers were retrospectively included (N.

Use of Omniflow® II Biosynthetic Graft for the Treatment of Vascular Graft and Endograft Infections.

Background: Vascular graft/endograft infection is a rare but life-threatening complication of cardiovascular surgery and remains a surgical challenge. Several different graft materials are available for the treatment of vascular graft/endograft infection, each having its own advantages and disadvantages. Biosynthetic vascular grafts have shown low reinfection rates and could be a potential second best after autologous veins in the treatment of vascular graft/endograft infection.

Is there a relation between type of primary melanoma treatment and the development of intralymphatic metastasis? A review of the literature.

Background: Intralymphatic metastases (ILM) originate from tumor cell emboli entrapped in dermal lymphatics between primary tumor and regional lymph node basin. Because of this origin, sentinel lymph node biopsy (SLNB) might increase ILM by restricting lymph flow.

Methods: Pubmed, Embase, Cochrane and Medline were searched for articles on ILM between 1980 and September 2014.

Tumor mitotic rate added to the equation: melanoma prognostic factors changed? : a single-institution database study on the prognostic value of tumor mitotic rate for sentinel lymph node status and survival of cutaneous melanoma patients.

Background: This study aimed to investigate the predictive value of the tumor mitotic rate per mm(2) (TMR) for sentinel lymph node (SLN) status and survival in intermediate and thick cutaneous melanoma.

Methods: Patients treated for stage I and II melanoma with wide local excision and SLN biopsy between May 1995 and May 2013 were analyzed. In case of insufficient data regarding TMR, pathology slides were reanalyzed.

Cutaneous melanoma: medical specialists' opinions on follow-up and sentinel lymph node biopsy.

Background: The purpose, frequency and content of follow-up (FU) visits have been widely debated for all common malignancies, including melanoma. The aim was to gain insight into Dutch medical specialists' opinions on melanoma FU and to assess their views on sentinel lymph node biopsy (SLNB).

Methods: All members of the Dutch Society of Surgical Oncology and the Dutch Society of Dermatology and Venereology were invited to complete a web-based questionnaire, consisting of 25 questions addressing the following topics: 1) respondent characteristics, 2) knowledge of national melanoma guideline, 3) opinions on melanoma FU, and 4) view on the significance of SLNB.

S-100B: a stronger prognostic biomarker than LDH in stage IIIB-C melanoma.

Background: In melanoma patients with nodal macrometastases, the distinction between good and poor prognosis is based on the presence of primary melanoma ulceration or metastatic involvement of 4 or more lymph nodes in the 7th edition of the American Joint Committee on Cancer (AJCC) classification. We hypothesized that biomarkers would increase the accurateness of staging in these patients. The aim was to assess and compare the prognostic impact of biomarkers S-100B and LDH and to determine the best timing of their measurement in stage IIIB-C melanoma.

Effectiveness of different footbathing frequencies using copper sulfate in the control of digital dermatitis in dairy cows.

Two experiments were conducted to test the effectiveness of different footbathing frequencies using CuSO₄ in the control of digital dermatitis (DD) in groups of dairy cows with low and high DD prevalence in an endemically infected herd. During the study, groups of cows walked through allocated footbath solutions after milking on 4 consecutive milkings each week, 2 wk, or monthly, depending on treatment. The footbath solutions were changed either after 200 cows had passed through the footbath or within 24 h.

Lymphatic drainage patterns from melanomas on the shoulder or upper trunk to cervical lymph nodes and implications for the extent of neck dissection.

Purpose: To determine the incidence and pattern of cervical lymphatic drainage in patients with melanomas located on the upper limb or trunk, and to evaluate our current neck dissection protocol for those patients with a N+ neck.

Methods: Of 1192 melanoma patients who underwent sentinel node biopsy, 631 were selected with a primary tumor on the upper limb or trunk. All lymphoscintigrams, SPECT/CT images and operative reports were reviewed to determine the exact locations of sentinel nodes visualized preoperatively and dissected during operation.

Use of S-100B to evaluate therapy effects during bevacizumab induction treatment in AJCC stage III melanoma.

Aim: To investigate the feasibility of using bevacizumab to improve the survival of American Joint Committee on Cancer (AJCC) stage III melanoma patients, we investigated how a single bevacizumab treatment affected nodal disease and a panel of biomarkers in clinically fluorodeoxyglucose positron emission tomography (FDG-PET)/computed tomography (CT)-staged, stage III melanoma patients, prior to therapeutic lymph node dissection (TLND).

Methods: Four weeks before TLND, nine patients (median age 50, range 28.8-62.

Long-term follow-up reveals that ulceration and sentinel lymph node status are the strongest predictors for survival in patients with primary cutaneous melanoma.

Purpose: To assess the long-term outcome after sentinel lymph node biopsy (SLNB) in melanoma patients.

Methods: Between 1995-2009 450 melanoma patients underwent SLNB in a single center. Survival and prognostic factors were analyzed for 429 patients.

The value of pre operative S-100B and SUV in clinically stage III melanoma patients undergoing therapeutic lymph node dissection.

Introduction: High preoperative serum S-100B values and Standardized Uptake Values (SUV) of Fluorodeoxyglucose (FDG) in PET for clinically stage III melanoma patients could be indicators of recurrence after surgical treatment. Aim was to assess the correlation and the prognostic value of these markers.

Methods: All melanoma patients with palpable nodal metastases, without distant metastases, were included from February 2004 to December 2007.

Effectiveness of different footbath solutions in the treatment of digital dermatitis in dairy cows.

Three experiments were conducted to test the effectiveness of different footbath solutions and regimens in the treatment of digital dermatitis (DD) in dairy cows. During the study, groups of cows walked through allocated footbath solutions after milking on 4 consecutive occasions. All cows were scored weekly for DD lesion stage on the hind feet during milking.

Effects of sire breed on ewe dystocia, lamb survival and weaned lamb output in hill sheep systems.

A study was carried out on six hill farms, located in the main hill regions of Northern Ireland, over three breeding seasons to investigate the effect of sire breed on ewe dystocia, lamb survival and weaned lamb output. On each farm, groups of 26 to 40 purebred Scottish Blackface ewes (n = 3174) were crossed with Blackface, Swaledale, North Country Cheviot, Lleyn and Texel sires by natural service (year 1) and artificial insemination (years 2 and 3). Each of the mating groups was initially balanced for ewe age, live weight and condition score, and a total of 15 sires of each breed were used over the 3 years.

Effects of genotype and plane of nutrition on growth and carcass characteristics of lambs from hill sheep systems.

The objective of this study was to determine the effect of lamb genotype and plane of nutrition on post-weaning lamb growth, and carcass characteristics in hill sheep systems. The lamb genotypes compared were as follows: purebred Scottish Blackface, Swaledale × Scottish Blackface, Cheviot × Scottish Blackface, Lleyn × Scottish Blackface and Texel × Scottish Blackface lambs. During the finishing period, lambs were allocated to a (i) low plane of nutrition (LP), based on a fixed allowance of dried grass pellets representing a grass-based system; (ii) high plane of nutrition (HP-cereal), with a diet consisting proportionately of 0.

Combined toxic effects of mycotoxins.

It is known for many years that several food items, derived from plants infected by fungi in the field during growing of the plant or during harvest and storage of the food item, can contain concomitantly different mycotoxins. As these combined mycotoxins occur simultaneously in the food item, consumption of the food will lead to a combined intake depending on the absorption rates of the different mycotoxins. Therefore, the question is justified whether such a combined intake of mycotoxins would lead to a possible higher risk for adverse health effects than the intake of one of these mycotoxins alone.