Publications by authors named "Speaker H"
Methamphetamine (METH) results in hyperthermia or hypothermia depending on environmental conditions. Here we studied the role of the β1 adrenergic receptor in mediating METH's temperature effects. Core temperature measurements were made telemetrically over a 7.
View Article and Find Full Text PDFRationale: Methamphetamine (METH) induces hyperthermia in warm and hypothermia in cool environments. Our first goal was to further study the role of ambient temperature in METH's effect on core temperature in rats. Previously, these effects were primarily demonstrated in high doses; we extended this investigation to the low-dose range (1 mg/kg METH).
View Article and Find Full Text PDFMethamphetamine (METH) changes core temperature and induces behavioral activation. Behavioral activation is also known to change core temperature. The purpose of this report was to 1.
View Article and Find Full Text PDFArticle Synopsis
- The study examines how methamphetamine (METH) affects core body temperature, focusing on how tolerance develops with chronic use and the role of ambient temperature.
- Rats were treated with varying doses of METH in controlled temperature settings, and their core temperatures were monitored for 12 days to assess changes over time and under different conditions.
- Findings indicate that peak temperature responses to METH occur at different times based on dosage, that chronic use leads to reduced temperature responses not linked to long-term neurochemical changes, and that the temperature response is characterized by two distinct phases due to different underlying mechanisms.