Prevalence and predictors of problematic tinnitus.

Objective: To determine the prevalence and characteristics of problematic tinnitus in a representative United States (US) sample.

Design: Cross-sectional study of the NHANES database from 2011-2012 and 2015-2016.

Study Sample: 8029 records were included for analysis.

Achieving Cochlear Therapeutic Hypothermia through Irrigation of the Mastoid and Tympanic Cavities.

Introduction: Mild therapeutic hypothermia (MTH) is an exciting nonpharmaceutical otoprotection strategy. In this study, we applied simple irrigation of the tympanic and mastoid cavities to understand the timing of both achieving MTH and recovery back to euthermic temperatures for application in the clinical setting.

Methods: Three human temporal bones were used in this study in the temporal bone laboratory.

Defining Hearing Loss Severity Based on Pure-Tone Audiometry and Self-Reported Perceived Hearing Difficulty: National Health and Nutrition Examination Survey.

Background:  There is a well-known metric to describe average/normal vision, 20/20, but the same agreed-upon standard does not exist for hearing. The pure-tone average has been advocated for such a metric.

Purpose:  We aimed to use a data-driven approach to inform a universal metric for hearing status based on pure-tone audiometry and perceived hearing difficulty (PHD).

Jackson Heart Study: Aggregate cardiovascular disease risk and auditory profiles.

Objectives: Evaluate the relationship between cardiovascular disease (CVD) risk factors and cochlear function in African Americans.

Methods: Relationships between hearing loss, cochlear function, and CVD risk factors were assessed in a cross-sectional analysis of 1106 Jackson Heart Study participants. Hearing loss was defined as puretone average (PTA) > 15 dB HL.

Achieving Mild Therapeutic Hypothermia in the Human Cochlea.

Objective: To determine temperature and duration of cooling necessary for achieving cochlear mild therapeutic hypothermia (MTH) via ear canal cooling using cool water and earmold attached to a Peltier device.

Study Design And Setting: Human temporal bone lab study performed at the University of Mississippi Medical Center.

Interventions: Cochlear cooling via the ear canal using water irrigation and an earmold attached to a Peltier device.

New horizons in holistic, person-centred health promotion for hearing healthcare.

Over the course of a lifetime, the risk of experiencing multiple chronic conditions (multimorbidity) increases, necessitating complex healthcare regimens. Healthcare that manages these requirements in an integrated way has been shown to be more effective than services that address specific diseases individually. One such chronic condition that often accompanies ageing is hearing loss and related symptoms, such as tinnitus.

Emerging and established therapies for chemotherapy-induced ototoxicity.

Purpose: Ototoxicity is considered a dose-limiting side effect of some chemotherapies. Hearing loss, in particular, can have significant implications for the quality of life for cancer survivors. Here, we review therapeutic approaches to mitigating ototoxicity related to chemotherapy.

Oxymetazoline vs ofloxacin vs ciprofloxacin/dexamethasone- effects of drops on tympanostomy tube postoperative otorrhea.

Objective: To assess for differences in postoperative otorrhea rates after tympanostomy with tube placement surgery comparing use of oxymetazoline, ofloxacin, or ciprofloxacin/dexamethasone drops prescribed in the postoperative period.

Methods: A retrospective review was conducted of 516 pediatric patients who had either bilateral or unilateral myringotomy with tube placement performed during the year 2018. Information collected from each surgery included whether there was effusion at time of surgery, type of effusion, whether an adenoidectomy was performed the same time or prior, prior history of tube placement, style of tube placed, type of drop given or prescribed on the day of surgery.

Hearing Screening Age Considerations for Adults: National Health and Nutrition Examination Survey.

Background: The United States Preventative Service Taskforce recently determined that there was insufficient evidence to recommend hearing screening in adults.

Purpose: To determine the age to screen adults in the U.S.

Tobacco, but Neither Cannabis Smoking Nor Co-Drug Use, Is Associated With Hearing Loss in the National Health and Nutrition Examination Survey, 2011 to 2012 and 2015 to 2016.

Introduction: A relationship between tobacco smoking and hearing loss has been reported; associations with cannabis smoking are unknown. In this cross-sectional population-based study, we examined relationships between hearing loss and smoking (tobacco, cannabis, or co-drug use).

Methods: We explored the relationship between hearing loss and smoking among 2705 participants [mean age = 39.

Central Auditory Processing and the Relationship to Perceived Hearing Difficulty: The Jackson Heart Study.

Objective: There are limited population-based studies of central auditory processing (CAP). We aimed to determine the relationship between CAP measures and perceived hearing difficulty (PHD) despite normal pure-tone audiometry in an African-American population.

Study Design: Cross-sectional.

Otoscopy and tympanometry outcomes from the National Health and Nutrition Examination Survey (NHANES).

Purpose: The purpose of the study was to estimate the prevalence of conductive pathologies based on tympanometric and otoscopic findings in adults in the U.S. and examine relationships between abnormal findings and audiometrically defined or reported perceived hearing loss and tinnitus.

Mild Therapeutic Hypothermia and Putative Mechanisms of Hair Cell Survival in the Cochlea.

Sensorineural hearing loss has significant implications for quality of life and risk for comorbidities such as cognitive decline. Noise and ototoxic drugs represent two common risk factors for acquired hearing loss that are potentially preventable. Numerous otoprotection strategies have been postulated over the past four decades with primary targets of upstream redox pathways.

The Acute Effects of Time-Varying Caloric Vestibular Stimulation as Assessed With fMRI.

We describe preliminary results from the application of time-varying caloric vestibular stimulation (tvCVS) to volunteers during a continuous blood oxygen level dependent (BOLD) functional MRI (fMRI) acquisition, recording baseline, during-tvCVS and post-tvCVS epochs. The modifications necessary to enable the use of this novel device in a 3-Tesla magnetic field are discussed. Independent component analysis (ICA) was used as a model-free method to highlight spatially and temporally coherent brain networks.

Enhanced Recovery After Surgery Nutrition Protocol for Major Head and Neck Cancer Surgery.

Objective: To determine whether an enhanced recovery after surgery (ERAS) nutrition protocol is reasonably possible among our head and neck cancer (HNC) population with respect to system feasibility and patient compliance. Second, we aim to identify improvements in patient outcomes as a result.

Methods: Preexperimental research design among patients undergoing major HNC surgery after implementation of the ERAS nutrition protocol from July 2018 to July 2019 as quality improvement (QI).

Association Between Cardiometabolic Factors and Dizziness in African Americans: The Jackson Heart Study.

Background: Balance dysfunction is a complex, disabling health condition that can present with multiple phenotypes and etiologies. Data regarding prevalence, characterization of dizziness, or associated factors is limited, especially in an African American population.

Purpose: The aim of the study is to characterize balance dysfunction presentation and prevalence in an African American cohort, and balance dysfunction relationship to cardiometabolic factors.

A clinically derived guinea pig dosing model of cisplatin ototoxicity.

The guinea pig is a commonly-used animal model in hearing research, as their audible frequency range is similar to that of humans, and they possess comparatively large cochleae among rodents. Numerous studies have investigated the ototoxic effects of cisplatin in guinea pigs, but these have been mostly limited to single high-dose bolus injections of cisplatin. This method of drug administration is not consistent with human treatment schedules, and therefore lacks translational value to clinical applications.

Cool OtOprotective Ear Lumen (COOL) Therapy for Cisplatin-induced Hearing Loss.

Hypothesis: Localized cooling of the external ear has a protective effect on the susceptibility to cisplatin-induced hearing loss.

Background: We previously demonstrated significant protection from cisplatin-induced hearing loss using cool water ear canal irrigation. However, the study was limited to a single bolus injection of cisplatin and an acute time period.

Feasibility of Implementing Opioid Stewardship Recommendations for Sinonasal Surgery.

Objective: The objective of our study was to review the current literature pertaining to perioperative opioids in sinus surgery and to determine the effects of implementing opioid stewardship recommendations in the setting of endoscopic sinonasal surgery.

Study Design: Single-institution retrospective case-control study.

Setting: Academic medical center outpatient area.

Pediatric orbital floor fractures and the oculocardiac reflex: Experience from a level I trauma center.

Purpose: The purpose of this study is to determine whether bradycardia associated with the oculocardiac reflex is a significant source of morbidity in the post injury period following orbital floor fractures in children.

Materials/methods: A retrospective review of all pediatric patients who presented to our emergency department with an orbital floor fracture from May 1, 2016 to June 1, 2018 were included. Basic demographic data was collected as well as mechanism of injury, presence of bradycardia, and time to operating room.

Otologic and Audiologic Considerations for COVID-19.

The COVID-19 pandemic has created a number of considerations for otolaryngology; anosmia and ageusia in particular have gained significant attention. Here we present considerations in regard to treatment with quinine-derived drugs and the influence of masks on communication.

Stroke risk in African Americans with subclinical auditory dysfuntion evidenced by Distortion Product Otoacoustic Emissions: the Jackson heart study.

Distortion product otoacoustic emissions (DPOAEs) are sensitive to early indices of cochlear pathology. Pathology to the cochlea is in part mediated by ischaemic related mechanisms. We propose that DPOAEs may provide an objective measure of cardiovascular risk.

Characteristics and considerations for children with ankyloglossia undergoing frenulectomy for dysphagia and aspiration.

Objective: The purpose of this study is to analyze the basic demographics of patients who underwent frenulectomy at our institution as well as additional considerations regarding age, location of procedure, and possible effects on aspiration.

Methods: A retrospective chart review was performed based on CPT codes for frenulectomy and basic demographic data was collected. Other information such as presenting symptoms, type of ankyloglossia, location of the procedure, and modified barium swallow study (MBSS) information were also obtained.