Publications by authors named "Soysal P"

Aim: Our aim was to identify multimorbidity clusters and, in particular, to examine their contribution to well-being outcomes among the oldest old in Germany.

Methods: Data were taken from the large nationally representative D80+ study including community-dwelling and institutionalized individuals aged 80 years and over residing in Germany (n = 8,773). The mean age was 85.

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Purpose: To determine prevalences of common geriatric syndromes in the setting of different normal ranges of serum sodium.

Methods: In this cross-sectional study, 2048 older adults (aged ≥ 60) who underwent comprehesive geriatric assessment between 2016 and 2023 in one geriatric outpatient clinic were evaluated. Patient groups included moderate hyponatremia (< 130 mEq/L, n = 28, 1.

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Background: There is debate as to the association between dehydration and malnutrition. Thus, this study aimed to investigate the correlation between dehydration and malnutrition and their impact on geriatric syndromes.

Methods: This cross-sectional study included older adults (≥60 years) who attended one outpatient geriatric clinic.

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Few multination-based studies have examined the longitudinal association between PA (physical activity) and persistence of supra-threshold depressive symptoms (SDS). This cohort study aimed to assess the influence of PA on persistence of SDS. Data were obtained from the Population Survey of Health, Ageing and Retirement in Europe (SHARE).

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Dysphagia is defined as difficulty in swallowing, while presbyphagia is described as a change in swallowing process in healthy older adults, which is a compensable physiological impairment and synonymous with dysphagia. Aging is a well-known risk factor for Alzheimer's disease (AD), and oropharyngeal dysphagia (OD) is a common condition in AD. Our study aims to compare OD in AD patients and older adults with presbyphagia (OAwP).

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Background: Relationship between dysphagia and dehydration has not been studied widely. The aim of this study is to determine the frequency of dysphagia and dehydration in geriatric outpatient clinic, to evaluate the relationship between these two conditions.

Methods: The cross-sectional study included 1345 patients.

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Article Synopsis
  • - The study investigates the link between dynapenic abdominal obesity (DAO) and disability in daily living activities among older adults in low- and middle-income countries, finding DAO increases the risk of disability by over twice compared to those without it.
  • - Based on data from over 20,000 adults aged 60 and above, DAO was defined by low handgrip strength and high waist circumference, with disability measured by difficulties in daily activities.
  • - Diabetes, hypertension, and angina were identified as significant mediators in the relationship between DAO and disability, highlighting the need for further research on how addressing DAO could mitigate disability risks in older populations.
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Aim: The aim of the present study was to examine the relationship between anemia and basic and instrumental activities of daily living in older male patients.

Methods: A total of 223 older males attending one geriatric outpatient clinic were included in this cross-sectional study. Anemia was defined as a hemoglobin level below 13 g/dL.

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Background: There is a lack of studies investigating death anxiety among the oldest old based on a large, nationally representative sample during the pandemic. Thus, our aim was to investigate the prevalence and determinants of death anxiety among the oldest old in Germany during the Covid-19 pandemic.

Methods: Cross-sectional data were taken from the 'Old Age in Germany' (D80+) study.

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Article Synopsis
  • Vision impairment (VI) and eye diseases like cataracts and age-related macular degeneration (AMD) may be linked to problems with thinking and memory, but not much research has been gathered about this yet.
  • Researchers looked at many studies to see if there is any strong evidence connecting vision issues to dementia and other memory problems.
  • They found some suggestive links, particularly between cataracts and Alzheimer's disease, but overall, none of the evidence was super strong or certain.
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Objectives: To examine the association between perception of one's social environment (in terms of residential attachment and neighborhood trust) and loneliness among the oldest old and whether these associations differ by living arrangement.

Methods: We used data from the nationally representative "Old Age in Germany (D80+)" study that included individuals residing in private households and institutionalized settings. The analytic sample was 9,621 individuals (average age: 85.

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Aim: The aim of the present study was to examine the relationship between anemia and basic and instrumental activities of daily living in older female patients.

Methods: 540 older female outpatients were included in this cross-sectional study. Anemia was defined as a hemoglobin below 12 g/dL.

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Background And Aims: Increasing attention is being paid to the role of human papillomavirus (HPV) in men and specifically reproduction. Growing evidence suggests an association between HPV infection with many adverse effects including the impairment of semen parameters, the increase of blastocyst apoptosis, the reduction of endometrial implantation of trophoblastic cells, as well as the increase rate of miscarriages and spontaneous preterm birth.

Methods: We systematically searched PubMed/MEDLINE, Scopus, Embase, Web of Science, CINHAL, PsycINFO, and ERIC from inception to 2nd of July 2024, for studies that investigated the association between HPV infection with sperm parameters and fertility outcomes.

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Food insecurity, characterized by inadequate access to sufficient and nutritious food, poses a significant challenge to the health and well-being of older adults. This systematic review and meta-analysis was aimed to examine the association between food insecurity and body mass index (BMI) in older people, i.e.

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Background: Knee osteoarthritis (KOA) is a widespread chronic condition. Depression frequently occurs among patients with KOA. The objective of this meta-analysis was to identify risk factors associated with comorbid depression in patients with KOA.

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Article Synopsis
  • - Vaccine-associated rheumatic diseases (RADs) are rare but concerning adverse effects of vaccines, yet there's limited large-scale research on the topic, particularly since the COVID-19 pandemic began.
  • - A comprehensive study analyzed 131 million reports in the WHO's database from 1967 to 2023, finding an increase in RAD reports, particularly after 2020, mainly related to COVID-19 mRNA vaccines.
  • - The highest risk for RADs was linked to hepatitis B vaccines, followed by COVID-19 mRNA and anthrax vaccines, with young females and older males being more likely to report these adverse reactions.
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We investigated the association between sedentary behavior (SB) and wish to die (WTD; i.e., feeling that one would be better off dead or wishing for one's own death), and the extent to which this can be explained by sleep problems, depression, anxiety, loneliness, perceived stress, and social network in a nationally representative sample of adults aged ≥50 years from Ireland.

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Purpose: To evaluate diabetic retinopathy (DR) screening global adherence rate and the association between sociodemographic and clinical variables and adherence rates to DR screening in individuals with diabetes.

Design: Systematic review and meta-analysis.

Methods: This systematic review was registered with International Prospective Register of Systematic Reviews (ID: CRD42024507035).

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Purpose: Zoledronic acid can inhibit the activity of osteoclasts, and thus, may slow or inhibit bone loss. The purpose of this study was to systematically evaluate the efficacy and safety of zoledronic acid in the treatment of osteoporosis.

Methods: Four databases, PubMed, Embase, Cochrane Library, and Web of Science, were systematically searched up to December 26, 2022.

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Background: The association between depression and dementia is still unclear, particularly regarding depression as a potential risk factor preceding dementia. Therefore, we aimed to verify if the presence of depression at baseline may increase the risk of dementia and cognitive impairment during 15 years of follow-up in the SHARE (Survey of Health, Aging and Retirement in Europe) study.

Methods: Depressive symptoms were defined using the EURO-D, with a score ≥4 indicative of depression.

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Background: Cataracts may increase risk for falls but studies on this topic from low- and middle-income countries (LMICs) are scarce. Therefore, we examined the cross-sectional association between self-reported visual symptoms (suggesting cataract) and self-reported injurious falls in nationally representative samples of adults aged ≥ 65 years from five LMICs (China, Ghana, India, Mexico, and Russia).

Methods: Data from the WHO Study on global AGEing and adult health (SAGE) were analysed.

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Background: The present study aimed to investigate the association between COVID-19 and the cumulative incidence of depression and the potential role of sick leave in a large representative sample of German adults.

Methods: This retrospective cohort study was based on the Disease Analyzer database (IQVIA) data. This study included individuals aged ≥16 years with a COVID-19 diagnosis in 1284 general practices in Germany between March 2020 and December 2021, and the propensity score matched cohort without COVID-19.

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Article Synopsis
  • This study explored the link between dehydration and major neurocognitive disorder (MND) in older adults, focusing on different types of dementia.
  • Among 1377 patients over 65, dehydration was found to be more prevalent in those with dementia compared to those without, with specific rates depending on the type of dementia.
  • The findings suggest that while dehydration is associated with MND, it is also common in older individuals without cognitive impairments, highlighting the importance of monitoring hydration in this population.
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