Publications by authors named "Soyeon Yi"
Article Synopsis
- Extracellular vesicles (EVs) from Lactobacillus reuteri (L. reuteri), a probiotic, show potential as an effective cancer treatment when taken orally, demonstrating stability in the digestive tract.
- In lab studies using A549 cancer cells and mice, L. reuteri-derived EVs (REVs) were found to activate apoptosis and enhance the effectiveness of other cancer drugs.
- In a mouse model, REVs combined with photothermal therapy completely eliminated tumors in 32 days, highlighting their promise as a standalone or adjunct treatment for cancer.
Listeria monocytogenes, a severe foodborne pathogen causing severe diseases underscores the necessity for the development of a detection system with high specificity, sensitivity and utility. Herein, the PoreGlow system, based on split green fluorescent protein (GFP), was developed and assessed for the fast and accurate detection of L. monocytogenes.
View Article and Find Full Text PDFClustered regularly interspaced short palindromic repeats (CRISPR)-based diagnostics have emerged as next-generation molecular diagnostics. In CRISPR-based diagnostics, Cas12 and Cas13 proteins have been widely employed to detect DNA and RNA, respectively. Herein, we developed a novel hybrid Cas protein capable of detecting universal nucleic acids (DNA and RNA).
View Article and Find Full Text PDFHeart disease is the leading cause of mortality in the U.S. with approximately 610,000 people dying every year.
View Article and Find Full Text PDFPurpose: This study was designed to evaluate the effect of microgravity on the diurnal variation of intraocular pressure (IOP).
Methods: IOPs were measured with the pressure phosphene tonometer in 1 subject (the first Korean astronaut) during spaceflight. IOPs were measured every 3 hours during day time (6 times per day) at 2 separate days in space with 3 repeated measurements at each time on both eyes.