Publications by authors named "Sowmya Nagarajan"

Article Synopsis
  • * The review explores allergen immunotherapy (AIT) as the only disease-modifying treatment for IgE-mediated allergic diseases, detailing its two main forms: subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT).
  • * AIT has been shown to effectively alleviate AC symptoms, reduce medication needs, and enhance quality of life, with SLIT noted for its better safety profile and overall long-term benefits.
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The current study proposes an empirical formula for absorption buildup factors as a function of target thickness. The present formula produces absorption buildup factors of compounds and mixtures with simple inputs of linear attenuation coefficient (μ), tenth value layer (TVL) and half value layer (HVL) of interacting target for the atomic number region 29 < Z < 92 for the energies 0.2 MeV < E < 1.

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We investigated different decay modes such as heavy particle radioactivity (HPR), spontaneous fission (SF), alpha decay and beta-decay in superheavy (SH) region 104 ≤ Z ≤ 126. In HPR, different emissions from Zmin = 28 to maximum heavy particle (HP) emission up to Zmax = Z - 82 were considered. In the evaluation of Q-values, mass excess Weizsäcker-Skyrme 4+radial basis function (WS4+RBF) values were taken into account.

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In outer space, we find many types of radiations that are due to solar flares, radiation belt, cosmic rays, etc. We are fortunate enough to be protected from these radiations on the surface of the Earth, whereas in other celestial objects such as planets and satellites, without a protecting atmosphere, penetration of radiation that may be ionising or non-ionising is inevitable. Hence, studying radiation environment and its effect on such celestial objects is very important for establishing facilities such as satellites, payloads, vehicles and human exploration.

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India is a low-middle income country with a population of 1.4 billion and home to one quarter of the world's children. Exclusive breastfeeding until 6 months and continued breastfeeding until at least 2 years as per global recommendations are common practice.

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Justification: Rising air pollution is an ever-growing threat to many human diseases. Poor air quality has been directly correlated with respiratory allergies with a disproportionate affection among the pediatric age group. A clear understanding of common air pollutants and their potential contribution in allergic rhinitis and asthma is lacking.

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Keratoconus (KC) is an ectatic disease of the cornea characterized by localized thinning and protrusion causing irregular astigmatism, which can lead to significant visual impairment. KC has often been associated with allergy and/or atopy, which are immune-mediated inflammatory reactions primarily driven by IgE. A higher proportion of KC patients were reported to have history or suffer from systemic and/or ocular allergy with elevated allergen-specific IgE and/or total serum IgE.

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Purpose Of Review: Tuberculosis (TB) is the commonest infectious cause of death globally. Adverse reactions to first-line tuberculosis antibiotics are common and have a major impact on the outcomes of patients as second-line antibiotics are less effective and more toxic. The present review addresses the most recent literature regarding epidemiology, investigating reactions, and reintroducing treatment in patients who have had their treatment interrupted.

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It is generally accepted that allergic diseases are not curable and not preventable, but mainly controllable using pharmacotherapy (i.e. symptomatic medication).

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The plasmid hik31 operon (P3, slr6039-slr6041) is located on the pSYSX plasmid in Synechocystis sp. PCC 6803. A P3 mutant (ΔP3) had a growth defect in the dark and a pigment defect that was worsened by the addition of glucose.

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There are two closely related hik31 operons involved in signal transduction on the chromosome and the pSYSX plasmid in the cyanobacterium Synechocystis sp. strain PCC 6803. We studied the growth, cell morphology, and gene expression in operon and hik mutants for both copies, under different growth conditions, to examine whether the duplicated copies have the same or different functions and gene targets and whether they are similarly regulated.

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We have investigated the response of the cyanobacterium Synechocystis sp. PCC 6803 during growth at very low O2 concentration (bubbled with 99.9 % N(2)/0.

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