Publications by authors named "Sowmya A Nagarajan"

Article Synopsis
  • * The review explores allergen immunotherapy (AIT) as the only disease-modifying treatment for IgE-mediated allergic diseases, detailing its two main forms: subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT).
  • * AIT has been shown to effectively alleviate AC symptoms, reduce medication needs, and enhance quality of life, with SLIT noted for its better safety profile and overall long-term benefits.
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Justification: Rising air pollution is an ever-growing threat to many human diseases. Poor air quality has been directly correlated with respiratory allergies with a disproportionate affection among the pediatric age group. A clear understanding of common air pollutants and their potential contribution in allergic rhinitis and asthma is lacking.

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Keratoconus (KC) is an ectatic disease of the cornea characterized by localized thinning and protrusion causing irregular astigmatism, which can lead to significant visual impairment. KC has often been associated with allergy and/or atopy, which are immune-mediated inflammatory reactions primarily driven by IgE. A higher proportion of KC patients were reported to have history or suffer from systemic and/or ocular allergy with elevated allergen-specific IgE and/or total serum IgE.

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