Density-dependent population dynamic models strongly influence many of the world's most important harvest policies. Nearly all classic models (e.g.
View Article and Find Full Text PDFJ Eukaryot Microbiol
November 2024
Microsporidia are intracellular parasites that all possess a unique infection apparatus involving a polar tube. Upon contact with a host cell, this tube forms the conduit through which the parasite enters the host. Infecting mostly animals, microsporidian species can be transmitted vertically or horizontally, and exert various effects on their hosts: infections range from being relatively benign to lethal.
View Article and Find Full Text PDFThe safe administration of solid oral dose forms in hospital inpatients with swallowing difficulties is challenging. The aim of this study was to establish the prevalence of difficulties in swallowing solid oral dose forms in acute hospital inpatients. A point prevalence study was completed at three time points.
View Article and Find Full Text PDFIEEE Trans Vis Comput Graph
December 2024
The increasing ubiquity of data in everyday life has elevated the importance of data literacy and accessible data representations, particularly for individuals with disabilities. While prior research predominantly focuses on the needs of the visually impaired, our survey aims to broaden this scope by investigating accessible data representations across a more inclusive spectrum of disabilities. After conducting a systematic review of 152 accessible data representation papers from ACM and IEEE databases, we found that roughly 78% of existing articles center on vision impairments.
View Article and Find Full Text PDFIEEE Trans Vis Comput Graph
October 2023
Immersive analytics has emerged as a promising research area, leveraging advances in immersive display technologies and techniques, such as virtual and augmented reality, to facilitate data exploration and decision-making. This paper presents a systematic literature review of 73 studies published between 2013-2022 on immersive analytics systems and visualizations, aiming to identify and categorize the primary dimensions influencing their design. We identified five key dimensions: Academic Theory and Contribution, Immersive Technology, Data, Spatial Presentation, and Visual Presentation.
View Article and Find Full Text PDFIEEE Trans Vis Comput Graph
January 2023
Accessibility guidelines place restrictions on the use of animations and interactivity on webpages to lessen the likelihood of webpages inadvertently producing sequences with flashes, patterns, or color changes that may trigger seizures for individuals with photosensitive epilepsy. Online data visualizations often incorporate elements of animation and interactivity to create a narrative, engage users, or encourage exploration. These design guidelines have been empirically validated by perceptual studies in visualization literature, but the impact of animation and interaction in visualizations on users with photosensitivity, who may experience seizures in response to certain visual stimuli, has not been considered.
View Article and Find Full Text PDFIEEE Trans Vis Comput Graph
January 2023
Internet routing is largely dependent on Border Gateway Protocol (BGP). However, BGP does not have any inherent authentication or integrity mechanisms that help make it secure. Effective security is challenging or infeasible to implement due to high costs, policy employment in these distributed systems, and unique routing behavior.
View Article and Find Full Text PDFChlorinated paraffins (CPs) are synthetic chemicals that are produced at high volumes and have a global presence. CPs are generally divided into three groups based on their carbon chain lengths: short-chain CPs (SCCPs, C), medium-chain CPs (MCCPs, C), and long-chain CPs (LCCPs, C). SCCPs have been formally recognized as persistent organic pollutants (POPs) and have been listed under the Stockholm Convention on POPs.
View Article and Find Full Text PDFBackground: Anautogenous mosquitoes commonly consume nectars and other solutions containing sugar but are thought to only produce eggs in discrete gonadotrophic cycles after blood-feeding on a vertebrate host. However, some anautogenous species are known to produce eggs if amino acids in the form of protein are added to a sugar solution. Unclear is how different sources of amino acids in sugar solutions affect the processes that regulate egg formation and whether responses vary among species.
View Article and Find Full Text PDFMarkov chain Monte Carlo is the engine of modern Bayesian statistics, being used to approximate the posterior and derived quantities of interest. Despite this, the issue of how the output from a Markov chain is post-processed and reported is often overlooked. Convergence diagnostics can be used to control bias via burn-in removal, but these do not account for (common) situations where a limited computational budget engenders a bias-variance trade-off.
View Article and Find Full Text PDFTrypanosomatids (order Kinetoplastida), including the human pathogens (agent of Chagas disease), , (African sleeping sickness), and (leishmaniasis), affect millions of people and animals globally. is considered one of the least studied and most poorly understood tropical disease-causing parasites, in part because of the relative lack of facile genetic engineering tools. This situation has improved recently through the application of clustered regularly interspaced short palindromic repeats-CRISPR-associated protein 9 (CRISPR-Cas9) technology, but a number of limitations remain, including the toxicity of continuous Cas9 expression and the long drug marker selection times.
View Article and Find Full Text PDFBackground: The objective of this randomized trial was to evaluate the incidence of incisional hernia after transverse or vertical incisions for open aortic aneurysm repair.
Methods: The study group comprised 69 patients who underwent elective aneurysm repair between November 1998 and November 2000 (60 men, nine women; mean age 72.8 (range 56-95) years).
Aim: This prospective study was conducted to assess feasibility, patients' acceptability and impact of ultrasound screening on rupture rate of abdominal aortic aneurysms (AAAs).
Methods: A population based sample of men (n=2709), aged over 60 years, covering 11 general practices was offered ultrasound screening between January 1996 and December 2003. The presence of risk factors for arteriosclerosis and annual rupture rates for AAAs were analyzed.
Transcription factor oncogenes such as GLI and c-MYC are central to the pathogenesis of human tumors. GLI encodes a zinc finger protein that is activated by Sonic Hedgehog signaling. Mutations in this pathway induce GLI expression in basal cell carcinoma, and expression of GLI in mice is sufficient to induce these skin tumors.
View Article and Find Full Text PDFUrban violence, collision of high-speed vehicles, acts of terrorism and military conflict continue to present difficult arterial injuries. The immediate threat of exsanguination, combined often with multiple trauma, and the challenge of limb salvage makes speedy effective management essential to improve the outcome for victims, who are frequently young adults.
View Article and Find Full Text PDFPurpose: The original Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity and the more recent Portsmouth predictor equation for mortality scoring systems were developed to provide risk-adjusted mortality rates in general surgery. The aim of this study was to compare crude and risk-adjusted operative mortality rates among four surgeons using the above scoring systems and assess their applicability for patients scored retrospectively.
Methods: A total of 505 consecutive patients undergoing major gastrointestinal surgery were analyzed; 65 percent underwent colorectal, 27.
There exists a lack of understanding of normal preputial development which is reflected in the large numbers of inappropriate referrals for circumcision. While the scarred prepuce invariably responds best to formal circumcision a more conservative approach is recommended in those symptomatic patients with non-retractile foreskins. In this study, patients referred to the out-patient department with a phimosis were assessed.
View Article and Find Full Text PDFWe present a method of repair for large incisional hernias using lateral relieving incisions of the anterior rectus sheath. This is a modification of the methods previously described by Young (1), Hunter (2) and Maguire and Young (3). There were no recurrences in the 13 patients reviewed.
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