Publications by authors named "Sourour Moliavi"

Irradiation with electrons is the primary treatment regime for localized conjunctival low-grade lymphomas. However, radiation-induced cataracts are a major cause of treatment-related morbidity. This study investigates whether lens-sparing electron irradiation produces sufficient disease control rates while preventing cataract formation.

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Article Synopsis
  • - The study analyzed the effects of photon radiotherapy on orbital non-Hodgkin lymphomas by reviewing MRI data from 36 patients, focusing on tumor regression and how residual lesions influenced disease control using the Lugano classification.
  • - Results showed that a significant proportion (91.2%) of patients still had tumor remnants within the first six months post-treatment, with partial response rates declining over time at 12-24 months (75%) and beyond.
  • - Complete response rates varied according to the Lugano classification, showing 20% at 12-24 months and 50% at over 48 months, but progression-free survival rates were similar between groups, indicating that even small residual tumor volumes may remain long-term after
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We assessed the long-term outcomes and treatment-related adverse effects of patients with Stage I, "orbital-type" lymphomas that were uniformly treated with photons. All consecutive patients diagnosed with low-grade, Ann Arbor Stage IEA orbital lymphoma treated between 1999 and 2020 at our department were retrospectively reviewed. We excluded patients with exclusive conjunctival involvement, typically treated with en face electrons.

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