Introduction of the Trifluoropropionate Moiety into Aromatic Rings via Rhodium-Catalyzed Coupling of Arylboronic Acids with Diazoesters.

A catalytic method for the introduction of pharmaceutically meaningful fluorinated propionic acid side chains into aromatic compounds is presented. In the presence of rhodium catalyst [RhCp*Cl], various arylboronic acids are efficiently coupled with an easy-to-access diazoester reagent to give perfluorinated derivatives of phenylpropionic acids, including top-selling profen drugs. The key advantage of this approach is that the pharmacophore is introduced as a whole and is compatible with various functionalities and drug discovery.

Full Classification of Transport on an Equilibrated 5/2 Edge via Shot Noise.

The nature of the bulk topological order of the 5/2 non-Abelian fractional quantum Hall state and the steady state of its edge are long-studied questions. The most promising non-Abelian model bulk states are the Pfaffian (Pf), anti-Pffafian (APf), and particle-hole symmetric Pfaffian (PHPf). Here, we propose to employ a set of dc current-current correlations (electrical shot noise) in order to distinguish among the Pf, APf, and PHPf candidate states, as well as to determine their edge thermal equilibration regimes: full vs partial.

Floral scents, specialized metabolites and stress-response activities in Heritiera fomes and Bruguiera gymnorrhiza from Sundarban mangrove ecosystem.

Floral biochemistry and stress physiology is an underexplored aspect of mangroves, which should be investigated as part of preservation and restoration efforts. A thriving true mangrove tree (Bruguiera gymnorrhiza (L.) Lamk.

The Flower Colour Influences Spontaneous Nectaring in Butterflies: a Case Study with Twenty Subtropical Butterflies.

Butterflies have a wide spectrum of colour vision, and changes in flower colour influence both the visiting and nectaring (the act of feeding on flower nectar) events of them. However, the spontaneous behavioural response of butterflies while foraging on real flowers is less characterised in wild conditions. Hence, this study intends to investigate flower colour affinity in wild butterflies in relation to nectaring frequency (NF) and nectaring duration (ND).

Visible light photoredox-catalyzed arylative cyclization to access benzimidazo[2,1-]isoquinolin-6(5)-ones.

A photoredox-catalyzed arylative radical cascade involving -acryloyl-2-arylbenzoimidazoles and diaryliodonium triflates leading to the formation of a broad array of pharmaceutically important arylated-benzimidazo[2,1-]isoquinolin-6(5)-ones is described. Importantly, the synthesized benzimidazoisoquinolinones are amenable for further synthetic manipulation and allowed efficient access to benzimidazo-fused polycyclic heterocycles.

Obesity among Medical Students of a Medical College: A Descriptive Cross-sectional Study.

Introduction: The prevalence of overweight and obesity is increasing these days. The adverse effect of obesity can be seen in different physiological functions. Relative fat mass is a newly identified parameter to estimate whole body fat.

Metal accumulation and morphofunctional damage in coelomocytes of earthworm collected from industrially contaminated soil of Kolkata, India.

The current study is aimed to assess the ecotoxicological effects of toxic metals and seasonal shift of the physicochemical characteristics of soil in an endogeic earthworm Metaphire posthuma of industrially contaminated soil of Calcutta leather complex. The accumulation of cadmium, chromium, lead and mercury was quantitated in whole earthworms and coelomocytes. The accumulation of metals was derived to be high in the coelomocytes than whole earthworms.

Shift in phagocytosis, lysosomal stability, lysozyme activity, apoptosis and cell cycle profile in the coelomocytes of earthworm of polluted soil near a tannery field of India.

Calcutta Leather Complex of the state of West Bengal, India has been designated as an industrially active zone with around 400 active tannery units. This area spanning 4.5 km is surrounded by human habitation.

Comparison between the motor function of school-aged children with normal birth weight and children with low birth weight: a cross-sectional study.

Pal A, Manna S, Dhara PC. Comparison between the motor function of school-aged children with normal birth weight and children with low birth weight: a cross-sectional study. Turk J Pediatr 2019; 61: 374-385.