Publications by authors named "Sourabh Tyagi"
COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), lead to a global health crisis with a spectrum of clinical manifestations. A potentially vulnerable category for SARS-CoV-2 infection was identified in patients with other medical conditions. Intriguingly, parallels exist between COVID-19 and cancer at the pathophysiological level, suggesting a possible connection between them.
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- Oncogenes are important in making cancers, and certain drugs can stop these cancer processes by blocking the proteins they create.
- In chronic myeloid leukaemia (CML), a specific oncogene called BCR-ABL1 causes the cancer by producing a protein that helps cancer grow.
- New treatments for CML now focus on targeted therapy with tyrosine kinase inhibitors (TKIs), but researchers are also looking for new drugs and using tools like CRISPR/Cas9 to find better ways to cure CML.
Antimicrobial resistance (AMR) is a rising issue worldwide, which is increasing prolonged illness and mortality rates in the population. Similarly, bacteria have generated multidrug resistance (MDR) by developing various mechanisms to cope with existing antibiotics and therefore, there is a need to develop new antibacterial and antimicrobial agents. Biocompatible nanomaterials like graphene and its derivatives, graphene oxide (GO), and reduced graphene oxide (rGO) loaded with metal/metal oxide nanoparticles have been explored as potential antibacterial agents.
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