DelNido cardioplegia versus St Thomas cardioplegia solution in double valve replacement: a single centre experience.

Introduction: The role of cardioplegia cannot be underrated in cardiac surgery. St Thomas solution is the most widely used cardioplegic, but needs repeated dosing. Del Nido solution provides long duration of asystole with adequate protection; but has been used mainly in paediatric patients.

Evolutionary dynamics of the delayed replicator-mutator equation: Limit cycle and cooperation.

Game theory deals with strategic interactions among players and evolutionary game dynamics tracks the fate of the players' populations under selection. In this paper, we consider the replicator equation for two-player-two-strategy games involving cooperators and defectors. We modify the equation to include the effect of mutation and also delay that corresponds either to the delayed information about the population state or in realizing the effect of interaction among players.

Safety considerations for Health care Workers involved in Cytoreductive Surgery and Perioperative chemotherapy.

The combined modality treatment of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) has gained worldwide acceptance for management of selected patients with peritoneal metastases from various cancers. Cytoreductive surgery is performed with the goal of removing all macroscopic disease and is coupled with perioperative chemotherapy (POC) in the form of HIPEC with or without EPIC (early postoperative intraperitoneal chemotherapy) to deal with the microscopic residual disease. These treatments entail the use of cytotoxic drugs in the operation theatre or in the intensive care unit where they are not commonly used and put the healthcare workers participating in the treatment at risk of exposure.