Canthaxanthin Attenuates the Vascular Aging or Endothelial Cell Senescence by Inhibiting Inflammation and Oxidative Stress in Mice.

Background: Vascular endothelial dysfunction is an early phenotype of aging-related vascular dysfunction. Delaying vascular aging and preventing cardiovascular disease are major public health problems that urgently need to be solved. Scientists have studied various drugs to prevent the occurrence and progress of cardiovascular disease, but progress has been slow.

Cardiac regeneration in and : discrepancies and problems.

Two studies have recently focused on adult heart regeneration in . While we reported on cardiac myogenic regeneration in after injury, Marshall and colleagues found no regeneration in an injured heart in Here, we would like to join the discussion initiated by Marshall et al. who debated the methods and species differences in both studies.

Heart regeneration in adult after apical resection.

Background: Myocardium regeneration in adult mammals is very limited, but has enormous therapeutic potentials. However, we are far from complete understanding the cellular and molecular mechanisms by which heart tissue can regenerate. The full functional ability of amphibians to regenerate makes them powerful animal models for elucidating how damaged mature organs are naturally reconstituted in an adult organism.