Publications by authors named "Soundos Youssef"
Opportunities to improve the clinical management of skin disease are being created by advances in genomic medicine. Large-scale sequencing increasingly challenges notions about single-gene disorders. It is now apparent that monogenic etiologies make appreciable contributions to the population burden of disease and that they are underrecognized in clinical practice.
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- CD1a, located on skin Langerhans cells, presents lipid antigens, and this study investigates its role in recognizing microbial lipids from skin bacteria.
- Researchers found that T cells respond to the bacterial lipid phosphatidylglycerol (PG) and its modified form, lysylPG, especially abundant in Staphylococcus aureus.
- The results suggest that in patients with atopic dermatitis, there's an increase in T cells that respond to PG-related lipids, indicating a potential link between these lipids and the development of atopic dermatitis.
Use of sleeve gastrectomy in adolescents and young adults with severe obesity.
Curr Opin Pediatr
August 2020
Purpose Of Review: The prevalence of pediatric obesity and its associated complications is increasing around the world. Treatment of obesity is challenging and metabolic and bariatric surgery (MBS) is currently the most effective treatment for this condition. At this time, vertical sleeve gastrectomy (VSG) is the most commonly performed bariatric procedure in adolescents.
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