Protein Dynamics Influence the Enzymatic Activity of Phospholipase A/Acyltransferases 3 and 4.

Phospholipase A/acyltransferase 3 (PLAAT3) and PLAAT4 are enzymes involved in the synthesis of bioactive lipids. Despite sequential and structural similarities, the two enzymes differ in activity and specificity. The relation between the activity and dynamics of the N-terminal domains of PLAAT3 and PLAAT4 was studied.

Removal of slow-pulsing artifacts in in-phase N relaxation dispersion experiments using broadband H decoupling.

Understanding of the molecular mechanisms of protein function requires detailed insight into the conformational landscape accessible to the protein. Conformational changes can be crucial for biological processes, such as ligand binding, protein folding, and catalysis. NMR spectroscopy is exquisitely sensitive to such dynamic changes in protein conformations.

Asynchronous telepsychiatry in maharashtra, India: study of feasibility and referral pattern.

Context: There is a paucity of published telepsychiatry results in India.

Aims: This study was conducted to assess the feasibility of asynchronous telepsychiatry and to study the referral patterns.

Settings And Design: This study was conducted in the telemedicine unit of a tertiary care center and design was retrospective analysis of 94 cases, which were diagnosed and treated by telepsychiatry.