Publications by authors named "Soumit Sankar Mandal"
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Synopsis of recent research by authors named "Soumit Sankar Mandal"
- The research by Soumit Sankar Mandal focuses on the structural and functional characterization of proteins, particularly in understanding DNA-protein interactions, with studies on the Cren7 protein highlighting how mutations in aromatic amino acids influence DNA binding affinity and bending capability.
- Another significant area of Mandal's work involves the nanomechanical properties of proteins, specifically investigating the conformational changes in the substrate binding domain of Hsp70 through single-molecule force experiments, identifying mechanical units that play a role in its function.
- Additionally, Mandal explores the complex phenomenon of protein folding, particularly observing the knotting and unknotting behavior of polypeptides in single-molecule experiments, which presents challenges for traditional atomistic simulations in capturing the dynamic nature of such processes.
