Primary pericardial synovial sarcoma is extremely rare, with few published cases in the literature. We report the case of an adolescent aged 13 years with primary pericardial synovial sarcoma discovered during tamponade, confirmed by molecular biology, and for whom treatment combined radiosurgery and adjuvant chemotherapy. The particularity of the case we are reporting stems from the young age of our patient (13 years) as well as the duration of remission, which is quite long (21 months) prior to a superior mediastinal relapse compared to cases reported in the literature.
View Article and Find Full Text PDFThe breast angiosarcoma is an endothelial malign tumor. Its prevalence is about 0.04% of all breast malignant tumors.
View Article and Find Full Text PDFMYCN protooncogene status was assessed for the first time in Morocco in peripheral neuroblastic tumors, including neuroblastoma, ganglioneuroblastoma, and ganglioneuroma. Correlations with age at diagnosis, stage, mitosis-karyorrhexis index, differentiation, and Shimada histology were evaluated. Thirty-six formalin-fixed, paraffin-embedded peripheral neuroblastic tumor tissue specimens collected between 2007 and 2010 from the Pathology Department were assessed for MYCN amplification using fluorescence in situ hybridization.
View Article and Find Full Text PDFThe granular cell tumor of the breast (TCGS) is a rare benign tumor, which grows from Schwann cells. It can be confused with a cancerous tumor clinically and radiologically. Only the histological appearance can make the diagnosis.
View Article and Find Full Text PDFBackground: Peripheral neuroblastic tumors (pNTs), including neuroblastoma (NB), ganglioneuroblastoma (GNB) and ganglioneuroma (GN), are extremely heterogeneous pediatric tumors responsible for 15 % of childhood cancer death. The aim of the study was to evaluate the expression of CD44s ('s': standard form) cell adhesion molecule by comparison with other specific prognostic markers.
Methods: An immunohistochemical profile of 32 formalin-fixed paraffin-embedded pNTs tissues, diagnosed between January 2007 and December 2010, was carried out.
We report a case of a 19-year-old girl who presented with 5-year history of swelling of upper lip and fissured tongue treated with dapsone then oral steroids without any improvement. Clinical examination found peripheral facial nerve paralysis and Labial mucosa biopsy showed non-necrotizing giganto-epithelioid granuloma. Diagnosis of Melkersson-Rosenthal syndrome was retaind because of association of cheilitis, lingua plicata and facial paralysis.
View Article and Find Full Text PDFFine-needle aspiration cytology (FNAC) is a simple and safe procedure that has proven to be accurate in the diagnosis of a variety of neoplasms. It is performed in an outpatient setting, and results are routinely available within 24 hours. To evaluate the diagnostic value of FNAC in the assessment of lymph nodes, we conducted a prospective study of patients with no history of previews malignancy, who underwent FNAC of an enlarged lymph node, during the period of January 2010 through June 2011.
View Article and Find Full Text PDFBackground: Childhood Wilms tumor represents one of the challenge for pediatric oncologists in developing countries. We report the characteristics and treatment results of patients with Wilms tumor according to SIOP 9 protocol in Morocco.
Procedure: From January 1989 to December 2000, 86 children with Wilms tumor were admitted.
We report a case of myeloid sarcoma of the brain mimicking a meningioma on CT scan. The lesion was first morphologically misdiagnosed as a lymphoma, but correctly identified by using immunochemistry with anti-myeloperoxidase, anti-CD68, anti-CD15 antibodies. An acute myeloid leukemia was diagnosed 5 months later.
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