Publications by authors named "Souley Abdoulkadiri"

Continuous surveillance for foot-and-mouth disease (FMD) in endemic settings such as West Africa is imperative to support improved local and regional control plans, with the long-term goal of regional eradication. This paper describes the genetic characterization of FMD viruses (FMDV) obtained from outbreaks in Nigeria (n = 45) and Cameroon (n = 15) during 2016 and from archival samples (n = 3) retrieved from a 2014 outbreak in Nigeria. These viruses were analysed in the context of previously published FMDV sequences from the region.

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We report the genomes of four foot-and-mouth disease virus (FMDV) serotype SAT 1 topotype X isolates from Cameroon. The viruses were isolated from bovine epithelium collected during an outbreak in 2016. These novel sequences update knowledge of FMDV diversity in Central Africa and contribute to regional FMDV molecular epidemiology.

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Article Synopsis
  • African swine fever (ASF) is a deadly disease affecting pigs that has become a significant concern in sub-Saharan Africa since 1997, previously noted in Cameroon as early as 1982.
  • Between 2010 and 2018, research in Cameroon led to the confirmation of 428 ASF-positive samples and identified three variants of ASF virus genotype I, all linked to past outbreaks.
  • The study suggests that these virus variants share similarities with those from neighboring countries, indicating cross-border movement, and recommends joint control measures and farmer compensation to mitigate the disease's impact.
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Transboundary movement of animals is an important mechanism for foot-and-mouth disease virus (FMDV) spread in endemic regions, such as Cameroon. Several transboundary animal trade routes cross the Far North Region of Cameroon, and cattle moved on foot along these routes often come in contact with native (sedentary and transhumant) herds. The purpose of this study was to investigate the role of transboundary trade cattle in the epidemiology of FMDV in the Far North Region of Cameroon.

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  • - In May 2016, a deadly avian influenza (H5N1) outbreak was detected in a poultry farm in Yaoundé, Cameroon, leading to a 75% mortality rate among chickens and 21 confirmed outbreaks across multiple regions until March 2017.
  • - The outbreaks accounted for approximately 138,252 bird losses, with over 44,000 deaths from infection and nearly 94,000 birds culled to control the spread.
  • - The H5N1 viruses identified belong to genetic clade 2.3.2.1c and showed signs of genetic reassortment with H9N2, indicating the need for more data to trace its origin and evolution in the region.
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  • - Highly pathogenic avian influenza A(H5N8) viruses from clade 2.3.4.4 entered West Africa in late 2016 during bird migration.
  • - Genetic analysis of the complete genome of these viruses found in Cameroon in January 2017 showed that the viruses came from several different origins.
  • - The study indicates that both wild and domestic birds in Cameroon were affected by multiple introductions of these viral strains.
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Foot-and-mouth disease virus (FMDV) causes morbidity and mortality in a range of animals and threatens local economies by acting as a barrier to international trade. The outbreak in the United Kingdom in 2001 that cost billions to control highlighted the risk that the pathogen poses to agriculture. In response, several mathematical models have been developed to parameterize and predict both transmission dynamics and optimal disease control.

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Bovine Bacillus anthracis isolates from Cameroon were genetically characterized. They showed a strong homogeneity, and they belong, together with strains from Chad, to cluster Aβ, which appears to be predominant in western Africa. However, one strain that belongs to a newly defined clade (D) and cluster (D1) is penicillin resistant and shows certain phenotypes typical of Bacillus cereus.

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