Publications by authors named "Soukaina Bouamrane"
Article Synopsis
- - Cancer involves the uncontrolled growth of abnormal cells, with colon cancer specifically affecting the large intestine or rectum, leading to abnormal tissue growth.
- - Recent research has focused on targeting tubulin and microtubules for cancer treatment, with quinoline compounds showing significant effectiveness against colorectal cancer.
- - The study investigated thirty quinoline compounds as tubulin inhibitors using computational methods, revealing that T1, T2, and T3 are the most stable and promising candidates for treating colorectal carcinoma.
Fluconazole and Voriconazole are individual antifungal inhibitors broadly adopted for treating fungal infections, including Candida Albicans. Unfortunately, these medicines clinically used have significant side effects. Consequently, the improvement of safer and better therapy became more indispensable.
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- COVID-19 is a highly lethal RNA virus classified as a pandemic by WHO, with ongoing research into effective treatments.
- A study utilizing 3D-QSAR models like CoMFA and CoMSIA resulted in promising predictive values for carboxamides sulfonamide derivatives, which could lead to the development of new compounds with potential activity against COVID-19.
- Molecular docking simulations suggest that these new compounds demonstrate strong stability and binding affinity to the COVID-19 main protease, and they show favorable ADMET properties, indicating their potential as reliable inhibitors.