In situ and real time investigation of the evolution of a Pseudomonas fluorescens nascent biofilm in the presence of an antimicrobial peptide.

Against the increase of bacterial resistance to traditional antibiotics, antimicrobial peptides (AMP) are considered as promising alternatives. Bacterial biofilms are more resistant to antibiotics that their planktonic counterpart. The purpose of this study was to investigate the action of an AMP against a nascent bacterial biofilm.

In vitro activity of dermaseptin S4 derivatives against genital infections pathogens.

Objectives: Sexually transmitted infections present a great risk to the reproductive health of women. Therefore, female-controlled vaginal products directed toward disease prevention are needed urgently. In the present study, efforts were made to evaluate the antimicrobial potency of dermaseptin DS4, an antimicrobial peptide derived from frog skin.