Publications by authors named "Souhila Kecili"

Purpose: HLA-A29 is the main susceptibility factor for birdshot chorioretinitis (BSCR). Our study assessed the impact of the second HLA-A allele alongside HLA-A29 on BSCR severity and susceptibility, focusing on HLA-A29 homozygous patients and those with alleles from the HLA-Aw19 group.

Methods: We included 120 additional cases to our previous analysis of 286 patients with BSCR, all HLA-A29 positive.

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Purpose: Birdshot chorioretinitis (BSCR) is an ocular HLA-related disease with variable clinical progression. We examine the quality of life (QOL) of BSCR individuals aged ≥80 years, providing insights into the long-term disease impact.

Methods: We utilized data from the CO-BIRD cohort (ClinicalTrials.

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Article Synopsis
  • Birdshot chorioretinitis (BSCR) is a chronic eye disease that affects both central and peripheral vision, prompting a study on how patients' visual acuity and field change over time.* -
  • The study involved 447 patients and revealed that as the disease progressed, the best corrected visual acuity (BCVA) notably decreased, particularly after 11-15 years, and other visual field measurements worsened over longer durations.* -
  • Findings indicated significant variability in visual outcomes among patients, which tended to worsen with disease duration, underscoring the need for monitoring and understanding the long-term effects of BSCR.*
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Purpose: To assess the manifestations of birdshot chorioretinitis (BSCR) in patients aged 80 and over.

Design: Among patients with BSCR followed in the CO-BIRD prospective cohort (ClinicalTrials.gov Identifier: NCT05153057), we analyzed the subgroup of patients aged 80 and over.

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