Publications by authors named "Sotona O"

Article Synopsis
  • The study investigates the role of antioxidant enzyme gene expression in Crohn's disease (CD) by analyzing surgically removed intestinal tissues from 28 patients, focusing on both inflamed and normal areas.* -
  • Results showed significantly lower levels of SOD1 and GSR mRNA in inflamed tissues, suggesting a potential link between reduced antioxidant defenses and tissue damage in CD, while no significant differences were observed for other enzymes like SOD2 and GPX.* -
  • The findings indicate that antioxidant gene expression varies in CD, with decreased SOD1 and GSR possibly contributing to localized tissue injury from reactive oxygen species.*
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Article Synopsis
  • The study investigates a new method for predicting anastomotic leakage risk by monitoring levels of neopterin, tryptophan, and kynurenine in patients undergoing rectal resection for cancer.
  • Out of 42 patients, significant differences were found in urinary neopterin/creatinine ratios between those with and without complications, indicating a potential risk factor for leakage.
  • High preoperative levels of urinary neopterin may signal increased risk for anastomotic leakage, and abnormal neopterin levels in urine and drainage fluid could help identify this issue early in the recovery process.
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Introduction: Stage pN+ is a factor which determines the strategy for treatment of T3 rectal cancer. The sensitivity of preoperative imaging examinations revealing N+ is not entirely satisfactory. Risk factors that are associated with pT3pN+ stage and that are detectable by preoperative examination have not been reliably identified.

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Introduction: Pilonidal sinus is a skin disease affecting the sacrococcygeal region caused by chronic irritation of the skin by ingrowing hairs that get pushed into skin sinuses and follicles. The acute form of the disease which is presented by subcutaneous abscesses very often develops into chronic suppurative subcutaneous fistula. The incidence of pilonidal sinus is approximately 26/100,000 people.

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Introduction: Adult umbilical hernia is a common surgical condition in the fifth and sixth decade of life. Despite the high frequency of umbilical hernia repairs, disappointingly high recurrence rates after simple suture repairs are reported, amounting to 54%. In addition, it is reported that with the rising frequency of recurrences, the size of the hernial sac and gate gradually increases.

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The authors present a case of papillary adenoma of the extrahepatic biliary tract presenting as obstructive jaundice. The diagnosis was based on the endoscopic retrograde cholangiopancreatography (ERCP), and above all cholangioscopy findings. The patient was treated by bile duct resection with Roux-en-Y hepaticojejunostomy.

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Introduction: Natural Orifice Transluminal Endoscopic Surgery (NOTES) is a dynamically developing branch of miniinvasive surgery, whose aim is a minimazing abdominal wall injury. Many experimental studies describe the wide spectrum of the NOTES techniques in the animal model. The NOTES experiment begun in the porcine model for acquiring experience at the Surgical Departement in the University Hospital in Hradec Králové.

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Introduction: Precise evaluation of lymph nodes in the surgical specimen is crucial for the staging and subsequent decision about the adjuvant therapy in colorectal cancer. Prognosis of the patients can be assessed only in cases when at least 12 lymph nodes in the surgical specimen are examined.

Aim Of The Work: To evaluate the radicalism of resections for colorectal carcinoma after introducing laparoscopic approach.

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