Carotid endarterectomy remains the gold standard treatment for carotid stenosis. Although transfemoral carotid artery stenting is a valid alternative for high-surgical-risk patients, transcarotid artery revascularization (TCAR) has shown promising results. Clinical case: 68-year-old male with hypertension and chronic obstructive pulmonary disease who developed a stroke due to a severe high stenosis in the right internal carotid artery.
View Article and Find Full Text PDFSyphilis is a highly contagious infectious disease primarily transmitted through sexual contact, caused by Treponema pallidum, an anaerobic gram-negative bacterium. Oral manifestations are significant, with the oral cavity often being the first site to exhibit symptoms. This study aims to present the clinical manifestations of oral syphilis through a six cases diagnosed in a dental setting.
View Article and Find Full Text PDFBackground: Patient-reported outcomes measures (PROMs) are standardized self-administered tools that assess the patient's opinion on the level of health, quality of life, and disability among other aspects. The objective of this study was to gather information on physical and mental health in patients with major mental illness using PROMs.
Methods: This was an observational, naturalistic, prospective study carried out in adult stabilized outpatients attended at nine Adult Mental Health Centers in Barcelona, Spain.
Targeted therapy indications for actionable variants in non-small-cell lung cancer (NSCLC) have primarily been studied in Caucasian populations, with limited data on Latin American patients. This study utilized a 52-genes next-generation sequencing (NGS) panel to analyze 1560 tumor biopsies from NSCLC patients in Chile, Brazil, and Peru. The RNA sequencing reads and DNA coverage were correlated to improve the detection of the actionable exon 14 skipping variant (METex14).
View Article and Find Full Text PDFBackground: Peer support programs may be effective for supporting breastfeeding among diverse groups, and in reducing disparities. This study provides insight regarding the implementation and outcomes of a peer breastfeeding support program.
Research Aims: (1) to examine how participation affected the outcomes of breastfeeding motivation, confidence, and coping strategies; and (2) to evaluate satisfaction with the program.
Brain imaging performed in natural settings is known as mobile brain and body imaging (MoBI). One of the features which distinguishes MoBI and laboratory-based experiments is the body posture. Previous studies pointed to mechanical, autonomic, cortical and cognitive differences between upright stance and sitting or reclining.
View Article and Find Full Text PDFTissue Factor-Factor VII complex is essential in coagulation activation. Congenital factor VII deficiency is a rare disorder that has an autosomal recessive inheritance. Clinical presentations are heterogeneous, ranging from asymptomatic carriers to severe bleeding phenotypes with factor VII replacement therapy requirements.
View Article and Find Full Text PDFIntroduction: Regular assessment of motor impairments is crucial in people with haemophilic arthropathy (PwHA). This study aimed to determine if there are differences in 30-seconds sit-to-stand (30-STS) power and maximal voluntary isometric contraction (MVIC) of the knee extensors between PwHA and healthy control group (CG). The secondary aims were to investigate the correlation between 30-STS power and MVIC of knee extensors with clinical characteristics and to assess their effectiveness in identifying motor impairment in PwHA.
View Article and Find Full Text PDFIntroduction: Social adaptation is a multifaceted process that encompasses cognitive, social, and affective factors. Previous research often focused on isolated variables, overlooking their interactions, especially in challenging environments. Our study addresses this by investigating how cognitive (working memory, verbal intelligence, self-regulation), social (affective empathy, family networks, loneliness), and psychological (locus of control, self-esteem, perceived stress) factors interact to influence social adaptation.
View Article and Find Full Text PDFThe impact of climate change on the distribution of native species in the Neotropics remains uncertain for most species. is an endemic epiphytic orchid in Mexico, categorized as threatened. The objective of this study was to assess the effect of climate change on the natural distribution of and the capacity of protected areas (PAs) to safeguard optimal environmental conditions for the species in the future.
View Article and Find Full Text PDFMed Oral Patol Oral Cir Bucal
May 2024
Background: Dry socket (DS) or fibrinolytic osteitis is a relatively common complication that can occur following tooth extraction. This study aimed to determine the prevalence of DS and identify its associated predictive and mediating variables.
Material And Methods: This study is classified as prospective observational, cross-sectional, and multicenter.
Few studies have evaluated the efficacy of ceftazidime-avibactam (CA) for carbapenemase-producing Enterobacterales bacteremia (KPC-PEB) in high-risk neutropenic patients. This is a prospective multicenter observational study in high-risk neutropenic patients with multi-drug resistant Enterobacterales bacteremia. They were compared according to the resistance mechanism and definitive treatment provided: KPC-CPE treated with CA (G1), KPC-CPE treated with other antibiotics (G2), and patients with ESBL-producing Enterobacterales bacteremia who received appropriate definitive therapy (G3).
View Article and Find Full Text PDFHealth Econ Policy Law
January 2024
The Colombian health system has made a deep transition into managed competition since a major reform in 1993. A market for insurers was created, the consumer has free choice of insurer and a national-level equalisation fund distributes revenues via a per-capita payment. Fully subsidised insurance for the poor and informal, and a comprehensive standardised benefit package for subsidised and contributory schemes (both schemes covering 98 per cent of the population), has led to a low level of out-of-pocket expenses and high financial protection, as well as to reduced gaps in equity in access.
View Article and Find Full Text PDFSocial media have emerged as a promising communication channel for promoting breastfeeding among a new generation of mothers. Yet, there is no published study reporting the effects of a large-scale social media intervention on key breastfeeding-related perceptions, attitudes, and behaviors. As a component of its breastfeeding promotion campaign, the Women, Infants, and Children (WIC) program implemented a 12-month intervention using Facebook and Instagram and subsequently evaluated the outcomes by surveying WIC-participating women ( = 832) twice, immediately before and after the intervention.
View Article and Find Full Text PDFEmpathy is a complex and multifaceted phenomenon that plays a crucial role in human social interactions. Recent developments in social neuroscience have provided valuable insights into the neural underpinnings and bodily mechanisms underlying empathy. This methodology often prioritizes precision, replicability, internal validity, and confound control.
View Article and Find Full Text PDFBackground: This paper estimates spatial inequalities of Rheumatoid Arthritis (RA) in Colombia and explores correlates of those disparities from a health system perspective.
Methods: We apply descriptive epidemiology to healthcare administrative records for estimation of crude and age-standardized prevalences, and health systems thinking for identification of barriers to effective access in RA diagnosis.
Results: The crude and age-standardized RA prevalence for Colombia in 2018 is estimated at 0.
Purpose: This retrospective chart review study (GWEP20052) evaluated plant-derived highly purified cannabidiol (CBD; Epidyolex®; 100 mg/mL oral solution) use without clobazam as add-on therapy in patients aged ≥2 years with Lennox-Gastaut syndrome (LGS) or Dravet syndrome (DS) enrolled in a European Early Access Program.
Methods: Data were extracted from patient charts covering a period starting 3 months before CBD treatment and concluding after 12 months of CBD treatment, or sooner if a patient discontinued CBD or started clobazam.
Results: Of 114 enrolled patients, data were available for 107 (92 LGS, 15 DS) who received CBD without clobazam for ≥3 months.
Introduction: This study contributes to the advancement of the field of Sport for Development and Peace (SDP) research in Latin America and the Caribbean (LAC). There are still few studies on SDP programs in this region and it is important to document and understand the impacts of these programs on participants.
Methods: The present study is the result of a collaborative research that aims to describe the experiences and perceptions of Colombian youth and program managers who participated in an SDP program that took them from a local community sports club to the Olympic Games.
The stoichiometry of the components of hexacyanoferrate materials affecting their final porosity properties and applications in CO capture is an issue that is rarely studied. In this work, the effect that stoichiometry of all element components and oxidation states of transition metals has on the structures of mesoporous K or Na-cobalt hexacyanoferrates (CoHCFs) and CO removal is reported. A series of CoHCFs model systems are synthesized using the co-precipitation method with varying amounts of Co ions.
View Article and Find Full Text PDFInt J Environ Res Public Health
December 2022
College students face unique challenges that the consequences of COVID-19 might aggravate. To explore the pandemic's consequences on college students' well-being, we conducted an online survey with 634 students from a private university in Cali, Colombia. The study sought to assess students' well-being due to COVID-19, and to explore the mediating effects of optimism, gratitude, and emotional closeness on college students' well-being.
View Article and Find Full Text PDFPurpose Of Review: Appropriate use of opioid analgesics is a key concern within the field of pain medicine. Several methods exist to discourage abuse and facilitate effective treatment regimens. Pill counting is often cited as one such method and frequently employed in varying fashions within clinical practice.
View Article and Find Full Text PDFAim: To evaluate the effectiveness and tolerability of cannabidiol (CBD) in patients with developmental and epileptic encephalopathies, including Dravet syndrome (DS), and Lennox-Gastaut syndrome (LGS), in a Spanish Expanded Access Program (EAP).
Methods: This was a multicenter, retrospective, observational study of patients treated with purified CBD in 14 hospitals across Spain. Patients with (1) written informed consent and (2) at least 6 months follow-up before the closure of the database were included.
Background: Stroke is the third largest single cause of death in Chile, responsible for 7.3% of all deaths in 2019. Large declines in stroke mortality rates in most Latin American countries in recent decades have been reported.
View Article and Find Full Text PDFIntroduction: The multisystem inflammatory syndrome in children associated with SARS-CoV-2 (MIS-C) is cha racterized by a hyperinflammatory state resulting from a cytokine storm, evidenced by alterations in laboratory blood testing and acute-phase proteins.
Objective: to describe the clinical and labora tory characteristics of patients hospitalized due to MIS-C and identify predictive markers of severity.
Patients And Method: Retrospective study of 32 patients.