Publications by authors named "Soto D"

Wind turbines used to combat climate change pose a green-green dilemma when endangered and protected wildlife species are killed by collisions with rotating blades. Here, we investigated the geographic origin of bats killed by wind turbines along an east-west transect in France to determine the spatial extent of this conflict in Western Europe. We analysed stable hydrogen isotopes in the fur keratin of 60 common noctule bats (Nyctalus noctula) killed by wind turbines during summer migration in four regions of France to predict their geographic origin using models based on precipitation isoscapes.

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Objective: Adolescents are typically motivated to conform to peer influence, including substance use behaviors, and it is likely that adolescents who deviate from their peers' substance use behaviors might experience stress and anxiety.

Method: A mixed-methods approach was utilized to examine the relationship between peer e-cigarette and cannabis use and symptoms of generalized anxiety among a diverse sample of 12 grade students in Los Angeles County, California, USA ( = 1,867, = 17.04, SD = 0.

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Objective, Participants, & Methods: The COVID-19 pandemic has exacerbated mental health challenges of university students, staff, and faculty alike. We used linear mixed models to examine demographic predictors of, and change over time in, self-reported depression and anxiety symptoms of a cohort of university students and staff/faculty between surveys administered in August-November 2021 and December 2021-March 2022.

Results: Students who identified as "other" race/ethnicity, Lesbian Gay Bisexual or Queer, and female, reported high baseline levels of both depression and anxiety.

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The giant kelp Macrocystis pyrifera is categorized as a keystone species, forming highly productive forests that provide ecosystem services and host a remarkable marine biodiversity of macro and microorganisms. The association of microorganisms with the algae is close and can be functionally interdependent. The Magellan Strait, a natural marine passage between the Atlantic and Pacific oceans, harbours extensive giant kelp forests.

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Human activity recognition (HAR) using smartphone inertial sensors, like accelerometers and gyroscopes, enhances smartphones' adaptability and user experience. Data distribution from these sensors is affected by several factors including sensor hardware, software, device placement, user demographics, terrain, and more. Most datasets focus on providing variability in user and (sometimes) device placement, limiting domain adaptation and generalization studies.

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Interleukin-6 (IL6) is a cytokine mainly involved in inflammatory processes associated with various diseases, from rheumatoid arthritis and pathogen-caused infections to cancer, where malignant cells exhibit high proliferation and overexpression of cytokines, including IL6. Furthermore, IL6 plays a fundamental role in detecting and differentiating tumor cells, including colorectal cancer (CRC) cells. Therefore, given its range of biological activities and pathological role, IL6 determination has been claimed for the diagnosis/prognosis of immune-mediated diseases.

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  • The Basophil Activation Test (BAT) is identified as a key biomarker for predicting autoimmune chronic spontaneous urticaria (aiCSU), but its real-world application and relation to omalizumab therapy are still under-researched.
  • A study conducted between 2010 and 2024 analyzed the clinical and laboratory characteristics of patients with chronic spontaneous urticaria (CSU) based on their BAT results, collecting data on various biomarkers and treatment responses.
  • Results showed that BAT positive patients exhibited specific traits such as low IgE levels and higher positivity for markers like anti-thyroid peroxidase; notably, these patients experienced shorter effectiveness of omalizumab treatment, highlighting the importance of BAT in clinical settings.
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  • - The study investigates the role of duplicated genes in human brain evolution, focusing on genes that are uniquely expanded in humans and their potential contributions to neurological traits like language and cognition.
  • - By analyzing a complete human genome and using advanced methods, the researchers identified 213 duplicated gene families and narrowed it down to 362 paralogs that are highly expressed in the brain and associated with autism-related genes.
  • - The research also utilized zebrafish models to "humanize" certain genes, revealing key insights into their roles in brain development, such as their impact on brain size and synaptic signaling.
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The expansion of the human family, resulting in a human-specific paralog likely contributed to altered evolutionary brain features. The introduction of in mouse models is associated with changes in cortical neuronal migration, axon guidance, synaptogenesis, and sensory-task performance. Truncated SRGAP2C heterodimerizes with the full-length ancestral gene product SRGAP2A and antagonizes its functions.

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In recent years, greater focus has been paid to the mental health needs of children from minoritized racial backgrounds. The culturally specific needs of these children, however, are often not considered within standard mental health treatments for youth. Oriented in the ecological validity framework (Bernal et al.

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The United States Food and Drug Administration (FDA) and other agencies have warned e-cigarette to companies to stop selling vaping products that look like toys because these products could attract youth to nicotine use. The vaping industry has gone a step further, producing vaping devices that are fully functional video games. We have observed several new vaping devices that contain youth-oriented video games such as Pac-Man, Tetris, Mario, Q*bert, and virtual pets.

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Aging is often associated with a decrease in cognitive capacities. However, semantic memory appears relatively well preserved in healthy aging. Both behavioral and neuroimaging studies support the view that changes in brain networks contribute to this preservation of semantic cognition.

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Research shows the impact of cultural stressors (e.g. perceived discrimination, bicultural stressors, negative context of reception) on adolescents' psychosocial outcomes.

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  • Climate change is decreasing river runoff in Northwestern Patagonia (NWP), affecting coastal ecosystems over the past few decades.
  • Significant drops in streamflow were noted, especially in northern river basins, with changes in flow patterns moving south toward rivers with snowmelt influence.
  • The reduced freshwater input is leading to warmer surface temperatures and shallower haloclines in the inner sea, indicating a need for improved monitoring and management strategies to adapt to these environmental shifts.
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  • This study compared two fluid removal strategies for critically ill patients on mechanical ventilation: a traditional negative fluid balance approach and a newer method focusing on fluid responsiveness.
  • Results showed that patients in the fluid responsiveness group were able to wean off the ventilator significantly faster than those in the negative fluid balance group.
  • The fluid responsiveness approach also helped avoid metabolic issues like secondary alkalosis and hypokalemia, suggesting it may be a safer and more effective method for managing fluid overload in these patients.
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Importance: Postmastectomy radiation therapy (PMRT) improves local-regional disease control and patient survival. Hypofractionation (HF) regimens have comparable efficacy and complication rates with improved quality of life compared with conventional fractionation (CF) schedules. However, the use of HF after mastectomy in patients undergoing breast reconstruction has not been prospectively examined.

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Human cell line models, including the neuronal precursor line LUHMES, are important for investigating developmental transcriptional dynamics within imprinted regions, particularly the 15q11-q13 Angelman (AS) and Prader-Willi (PWS) syndrome locus. AS results from loss of maternal UBE3A in neurons, where the paternal allele is silenced by a convergent antisense transcript UBE3A-ATS, a lncRNA that terminates at PWAR1 in non-neurons. qRT-PCR analysis confirmed the exclusive and progressive increase in UBE3A-ATS in differentiating LUHMES neurons, validating their use for studying UBE3A silencing.

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  • Scientists study how animals change to survive in different places, which is really important for understanding biology.
  • They looked at chimpanzees, our closest relatives, who live in many types of environments like rainforests and savannahs.
  • By examining genetic information from wild chimpanzees, they discovered that some chimps have adapted to fight off malaria in similar ways to humans, showing how important genetic diversity is for endangered animals.
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  • The study investigates how mental health changes before and during the COVID-19 pandemic relate to COVID-19 death rates, focusing on geographic and racial/ethnic differences.
  • Research conducted in Los Angeles County revealed that mental health disparities worsened during the pandemic, particularly for Non-White residents in areas with high COVID-19 mortality.
  • The findings suggest a need for increased mental health support in high-mortality areas, emphasizing the importance of addressing the needs of racial and ethnic minorities.
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Although Black women face disproportionately high rates of gun violence and incarceration loss, there is a scarcity of culturally relevant interventions for this population. The aims of this study were to (a) examine the need for a culturally responsive, trauma-informed, and evidence-based grief intervention and to (b) identify key program components and considerations. Using a community-based participatory research framework, co-collaborators interviewed and surveyed 13 Black women who experienced gun violence and/or incarceration loss.

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Increasing forest structural complexity is becoming a common goal in forestry worldwide. However, the lack of empirical quantification clouds its implementation. Here we quantified the long-term effects (> 30 y) of partial harvest on stand structural complexity and net primary productivity using the east-west precipitation gradient (318-2508 mm, mean annual precipitation-MAP) of western Patagonian as a study system.

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Understanding how the human brain maps different dimensions of social conceptualizations remains a key unresolved issue. We performed a functional magnetic resonance imaging (MRI) study in which participants were exposed to audio definitions of personality traits and asked to simulate experiences associated with the concepts. Half of the concepts were affective (e.

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Environmental stimuli elicit drug craving and relapse in cocaine users by triggering the retrieval of strong cocaine-related contextual memories. Retrieval can also destabilize drug memories, requiring reconsolidation, a protein synthesis-dependent storage process, to maintain memory strength. Corticotropin-releasing factor (CRF) signaling in the basolateral amygdala (BLA) is necessary for cocaine-memory reconsolidation.

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