Publications by authors named "Sotirios Anastasiadis"
Article Synopsis
- The study investigates the reliability of diagnosing adrenal insufficiency (AI) in patients with cirrhosis by comparing total cortisol and free cortisol levels.
- Findings show that while some patients have low total peak cortisol, they do not have low free cortisol, indicating a mismatch in diagnosis methods.
- Results indicate that free cortisol levels are not linked to kidney or heart function problems, but lower levels are seen in patients with more severe liver disease, suggesting decreased synthesis rather than adrenal dysfunction.
Relative adrenal insufficiency (RAI) was demonstrated in patients with cirrhosis and liver failure. A relationship appears to exist between the severity of the liver disease and the presence of RAI. Neither the mechanism nor the exact prevalence of RAI is fully understood.
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