Clinicians' Perspectives on the Telehealth Serious Illness Care Program for Older Adults With Myeloid Malignancies: Single-Arm Pilot Study.

Background: Serious illness conversations may help patients avoid unwanted treatments. We previously piloted the telehealth Serious Illness Care Program (SICP) for older adults with acute myeloid leukemia and myelodysplastic syndrome.

Objective: In this study, we aimed to understand the experience of the telehealth SICP from the clinician's perspective.

Telehealth serious illness care program for older adults with hematologic malignancies: a single-arm pilot study.

Older patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) feel shocked and bewildered when diagnosed. Serious illness conversations (SICs) may increase disease understanding and preparations for the future. However, SICs often happen late, in part because of clinician-perceived patient discomfort.

Corticosteroid-induced hyperglycemia is increased 10-fold in patients with pemphigus.

This study aimed to highlight the importance of routine screening for hyperglycemia and to develop a standardized, evidence-based approach for the management of pemphigus patients on prolonged systemic corticosteroid (CS) therapy. A cross-sectional study was conducted in two university-affiliated teaching hospitals using a referred sample of 200 patients with a confirmed diagnosis of pemphigus vulgaris, pemphigus foliaceus, or mucous membrane pemphigoid. All patients were receiving systemic CS therapy.

Cost-utility of lumbar decompression with or without fusion for patients with symptomatic degenerative lumbar spondylolisthesis.

Background Context: The most common surgical treatment of symptomatic degenerative lumbar spondylolisthesis (DLS) is decompression and instrumented fusion. However, contemporary, midline-sparing, microdecompressive techniques have shown good results for selected patients with stable Grade 1 DLS. Growing concerns over the rising cost and rates of spinal fusion warrant both clinical and economic comparative effectiveness research in this common spinal diagnosis.

Comparison of the efficacy of three PubMed search filters in finding randomized controlled trials to answer clinical questions.

Objective: The aim of this study was to compare the performance of three search methods in the retrieval of relevant clinical trials from PubMed to answer specific clinical questions.

Methods: Included studies of a sample of 100 Cochrane reviews which recorded in PubMed were considered as the reference standard. The search queries were formulated based on the systematic review titles.

Promoting development and use of systematic reviews in a developing country.

Introduction: One major barrier to develop health systems is the limited capacity for conducting research and implementation of research findings. We assessed the views of researchers, decision makers and research policy makers on how the development and usage of evidence from systematic reviews can be promoted in a country with limited resources.

Methods: We surveyed 131 participants in six systematic review workshops for their views on important items influencing the production and usage of systematic reviews in a developing country.

Quality of life and life events of living unrelated kidney donors in Iran: a multicenter study.

Background: A controlled living unrelated kidney donors (LURDs) transplant program has been started from 1988 in Iran. We surveyed LURDs to investigate the extent to which they experienced stressful life events before donation and their quality of life after donation.

Methods: Five hundred donors were approached.

Dermatoglyphic asymmetry and hair whorl patterns in schizophrenic and bipolar patients.

Dermatoglyphic quantitative counts, asymmetry between two hands, and hair whorls were assessed in schizophrenic, bipolar and normal samples. Higher dermatoglyphic directional asymmetry and lower fluctuating asymmetry in bipolar patients support their hypernormal asymmetries. An inverse association between hair whorl location and dermatoglyphic asymmetry in schizophrenia may show a higher probability of lateralization problems.

Sources of knowledge in clinical practice in postgraduate medical students and faculty members: a conceptual map.

Objectives: To determine the most important knowledge sources that can influence clinical practice and to cluster them in conceptual groups based on their relative importance.

Methods: Faculty members, fellows and residents of a large teaching tertiary care hospital were asked to rate the importance of different resources in their daily clinical practice and their understanding of some common terms from evidence-based medicine. The knowledge sources were distributed in a two-dimensional map using multidimensional scaling and hierarchical cluster analysis.