In vitro antibacterial effect of forsterite nanopowder: synthesis and characterization.

The aims of this study were the preparation, characterization, and in vitro antibacterial activity evaluation of forsterite (FS, MgSiO) nanopowder obtained by two major methods, namely sol-gel (FSsg) and co-precipitation (FSpp). The main aim was to determine the influence of preparation methodologies on physical properties and in vitro antibacterial activity of obtained forsterite nanopowder. To assess the best working temperature for the preparation of FSsg and FSpp, the synthesis and thermal treatment conditions were optimized on the basis of thermal gravimetric (TG) and differential scanning calorimetric (DSC) analysis performed on the dried gel and dried co-precipitated solid, respectively.

Amoxicillin-loaded electrospun nanocomposite membranes for dental applications.

Electrospun nanocomposite matrices based on poly(ε-caprolactone) (PCL), nano-hydroxyapatite (nHAp) and amoxicillin (AMX) were designed and investigated for dental applications. nHAp provides good biocompatibility, bioactivity, osteoconductivity, and osteoinductivity properties, and AMX, as antibiotic model, controls and/or reduces bacterial contamination of periodontal defects while enhancing tissue regeneration. A series of polymeric nanocomposites was obtained by varying both the antibiotic and nHAp contents.

The interplay between NSAIDs and Candida albicans on the gastrointestinal tract of guinea pigs.

Recent studies suggest that Candida albicans colonization is associated with several gastrointestinal inflammatory disorders and is also responsible for the delay in ulcer healing. No data are reported about the effects of C. albicans on the nonsteroidal anti-inflammatory drugs (NSAIDs)-induced necroinflammatory lesions.