Publications by authors named "Sorenlis Gonzalez"
Pharmaceuticals (Basel)
July 2022
Article Synopsis
- A new Cu(I)-chloroquine complex was synthesized and found to substantially inhibit CQ-resistant malaria strains, outperforming traditional CQ and some other metal-CQ complexes.
- The copper(I) compounds demonstrated enhanced antiplasmodial activity by effectively interacting with critical molecular targets like ferriprotoporphyrin and DNA, which are vital for the malaria parasite's survival.
- Overall, these copper complexes show potential as more effective antimalarial agents than existing treatments, including chloroquine diphosphate.
