Resolvin D5 (RvD5) is a lipid mediator known for its anti-inflammatory properties and its ability to increase reactive oxygen species (ROS) during bacterial infections, which can be harmful.
In a study involving female hairless mice, RvD5 was administered before UVB exposure, leading to reduced skin swelling and oxidative stress by enhancing antioxidants and decreasing harmful oxidants.
The treatment also lowered the levels of inflammatory markers and cell counts, which ultimately resulted in less collagen degradation and skin damage from UVB exposure, suggesting that RvD5 could be a potential treatment for UVB-related skin issues.