Publications by authors named "Sopromadze M"

NO-therapy was used in 40 patients with purulent wounds of soft tissues. Bacteriological, cytological and morphological examinations demonstrated acceleration of wound process compared with control group (40 patients without NO-therapy). Laser doppler flowmetry demonstrated significant improvement of microcirculation in wound zone during NO-therapy.

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Based on planimetric, bacteriologic and histologic study high efficiency of local ozonotherapy of wound in combination with low-frequency ultrasound was demonstrated experimentally on rat model of infected purulent skin wound. This method was used in 45 patients with purulent wounds of soft tissues (postoperative, posttraumatic, burn, sore spot) that led to fast cleaning of wound surface, decrease of bacterial contamination and granulations. It permitted to eliminate inflammation and to create optimum conditions for wound closure.

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Examination of 307 patients with trophic and sluggish wounds showed that the use of a focussed carbohydrate laser beam with an energy density of 800-1000 J/cm2 makes it possible to remove pyonecrotic masses and microbial flora from the wound surface in one-stage, rapidly, without bleeding and without injury to the underlying healthy tissues and, in most cases, to make it sterile. A defocused beam of this laser applied locally with an energy density of radiation ranging from 0.5 to 2.

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The article presents results of treatment of 372 patients with purulent wounds. In 187 patients a helium-cadmium laser was used (main group); in 185 patients (control group) other methods were used. The comparison of terms of cleansing the wounds from pyo-necrotic masses, appearance of granulations, epithelization++ and terms of wound healing and periods of staying at the hospital has shown high efficiency of the helium-cadmium laser for the treatment of purulent wounds.

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