[The effectiveness of the use of local antibacterial drugs in the postoperative period in a patient with a neoplasm of the external auditory canal].

This article presents clinical case of external auditory canal osteoma and postoperative management of this patients. In this publication the etiology of this pathology, as well as the clinical manifestations that accompany this pathological condition are described. We present a literature review and our own experience of treatment this group of patients.

Safety of high-power short pulse single spot diode laser stapedotomy: an experimental animal study.

Background: We present a new method of diode laser stapedoplasty - high-power short-pulse mode with preliminary carbonization of the waveguide and a single spot of laser ablation.

Aims/objective: The aim of our research is the safety evaluation of presented mode 0.98 µm diode laser cochleostomy in guinea pigs.

[Conservative treatment of exacerbation of chronic purulent otitis media].

The Purpose Of The Work: Is to study the efficacy of treatment of exacerbation of chronic tubotympanic purulent otitis media with Otofa drug with the active substance Rifamycin.

Material And Methods: Performed a retrospective analysis of 37 medical histories of patients who applied to the otorhinolaryngology clinic with a diagnosis of exacerbation of chronic purulent tubotympanic otitis media in the period from January 2019 to December 2019.

Results: Noted relief of symptoms such as throbbing noise and pain in patients receiving the topical Otofa drug (active ingredient Rifamycin) by the 3th day of therapy.

Results from the Survey of Antibiotic Resistance (SOAR) 2014-16 in Ukraine and the Slovak Republic.

Objectives: To determine antibiotic susceptibility in isolates of Streptococcus pneumoniae and Haemophilus influenzae collected in 2014-16 from Ukraine and the Slovak Republic.

Methods: MICs were determined by CLSI broth microdilution and susceptibility was assessed using CLSI, EUCAST and pharmacokinetic/pharmacodynamic (PK/PD) breakpoints.

Results: S.

The microbiome of the maxillary sinus and middle nasal meatus in chronic rhinosinusitis.

Aim: This multicenter study was focused on the identification of the microorganisms inhabiting the maxillary sinus and middle nasal meatus in chronic rhinosinusitis.

Methodology: 112 middle meatus swabs and 112 maxillary sinus aspirates from 103 patients were available for culture.

Results: A total of 244 strains of microorganisms representing more than 50 families were identified in the maxillary sinus and middle nasal meatus (164 and 80, respectively).

[Impact of renal dysfunction on clinical course of myocardial infarction complicated by acute heart failure in patients with preserved systolic function].

Aiming to assess the relationships between renal function and ST-segment elevation myocardial infarction (MI) clinical course and remote outcomes in patients with preserved systolic left ventricular (LV) function (LV ejection fraction > 40%) estimated glomerular filtration rates (eGFR) were evaluated on 1st and 3rd -10th MI day (n = 491). On 3rd-10th day of MI in patients with acute heart failure (HF) symptoms on admission day (1st group, n = 153) eGFR < 70 ml/min x per body surface unit was independent marker of re-infarction (Hazzard Ratio (HR) with 95% confidence intervals (95% CI) = 4,08 [1,72 -11,73], P < 0,01) and cardiovascular death (CVD) (HR [95% CI] = 3,61 [1,09 - 11,99], P = <0,05) during three years of follow-up. In patient without acute HF (2nd group, n = 338) eGFR < 68 ml/min was predictive of CVD within three years post-MI (HR [95% CI] = 7,13 [2,06 - 24,74], P = 0,002).

[Two cases of rare atypical localization of the petrosquamosal venous sinusis in the patients presenting with chronic suppurative epitympanitis complicated by cholesteatoma].

The authors report their original observations of rare and difficultto diagnose atypical localization of the petrosquamosal venous sinusis in the patients presenting with chronic suppurative otitis media. Such localization of this sinus was shown to hamper surgical interventions for sanative treatment.

[External granulation otitis].

The authors repot two cases of successful treatment of external granulation otitis. Taken together, the difficulties encountered in diagnostics of this condition, concomitant disorders aggravating pathological changes in the ear, and the malignant clinical course of the disease hamper the adequate management of external granulation otitis.

[Prophylaxis and treatment of complications after splenectomy performed for various diseases and trauma of the organ].

Analytic digest of the literature data and observations of their own were adduced, concerning the results of splenectomy (CE), performed for various indications. SE was performed in 2059 patients, including 1656--suffering the blood system diseases. After SE performance the occurrence of speciphic (the splenic fuction loss) and other severe postoperative complications is possible, severity of which depends on the main disease severity and the operation traumaticity.