Publications by authors named "Sophie VonDobschuetz"

Background: Middle East respiratory syndrome coronavirus (MERS-CoV) was identified in humans in 2012. Since then, 2605 cases and 937 associated deaths have been reported globally. Camels are the natural host for MERS-CoV and camel to human transmission has been documented.

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  • * A joint international project by OIE, FAO, and INTERPOL, launched in 2019, aims to enhance preparedness against agro-terrorism and agro-crime impacting animal health, with support from Canada.
  • * The project incorporates the FAO Surveillance Evaluation Tool (SET) and a new Biothreat Detection Module to assess countries' abilities to detect animal health threats, with a pilot implementation planned for early 2021.
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  • The pandemic caused by the coronavirus has highlighted the impact of the Coronaviridae family on human disease outbreaks, particularly with SARS-CoV-2 emerging in late 2019.
  • Due to limited knowledge about SARS-CoV-2's characteristics, researchers are exploring data from other coronaviruses to better understand their risks and effects.
  • The study reviewed infections from various coronaviruses in different species and aims to promote a One Health approach that integrates human, animal, and environmental health for better preparedness and response to future outbreaks.
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Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is an emerging viral disease and dromedary camels are known to be the source of human spill over events. A cross-sectional epidemiological surveillance study was carried out in Kenya in 2017 to, 1) estimate MERS-CoV antibody seropositivity in the camel-dense counties of Turkana, Marsabit, Isiolo, Laikipia and Nakuru to identify, and 2) determine the risk factors associated with seropositivity in camels. Blood samples were collected from a total of 1421 camels selected using a multi-stage sampling method.

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A cross-sectional study was conducted in Egypt to determine the prevalence of Middle East respiratory syndrome coronavirus (MERS-CoV) in imported and resident camels and bats, as well as to assess possible transmission of the virus to domestic ruminants and equines. A total of 1,031 sera, 1,078 nasal swabs, 13 rectal swabs, and 38 milk samples were collected from 1,078 camels in different types of sites. In addition, 145 domestic animals and 109 bats were sampled.

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Vaccination is the main tool implemented in Egypt since 2007 to control H5N1 avian influenza. The present study aimed at comparing the effectiveness of three avian influenza vaccination regimes in commercial broiler chickens carrying high levels of maternally derived antibodies (MDAs). Day-old chicks were divided into four experimental groups.

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The effectiveness of recombinant turkey herpesvirus avian influenza (A/swan/Hungary/4999/2006(H5N1)) clade 2.2 virus (rHVT-H5) vaccine was evaluated in two layer chicken breeds (White Bovans [WB] and Brown Shaver [BS]). One dose of rHVT-H5 vaccine was administered at day 1 and birds were monitored serologically (haemagglutination inhibition test) and virologically for 19 weeks.

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