Publications by authors named "Sophie Tardoski"
Article Synopsis
- * In studies with mice, the combination of US and the bisphosphonate zoledronate (ZOL) resulted in significantly smaller bone lesions and reduced tumor volumes compared to ZOL alone.
- * US helps release bisphosphonates from bone and enables deeper penetration into tumors, enhancing their anticancer activity and suggesting a new approach for improving treatment efficacy against bone-related cancers.
Ultrasound-mediated drug delivery is a field of research with promising results, although the exact mechanisms underlying intracellular delivery of therapeutic compounds remain to be elucidated. Many studies use drug carriers and cavitation to enhance drug uptake into tumor cells. However, cavitation could induce cell lysis and remain difficult to control and predict in vivo.
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