Publications by authors named "Sophie Scohy"
The appearance of new viruses and the cost of developing certain vaccines require that new vaccination strategies now have to be developed. DNA vaccination seems to be a particularly promising method. For this application, plasmid DNA is injected into the subject (man or animal).
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- Cyprinid herpesvirus 3 (CyHV-3) causes a serious disease in common and koi carp.
- A specific gene, ORF134, was studied and found to be a common protein in the virus that doesn't help it reproduce or make fish sick.
- The experiments using different virus types showed that fish got sick the same way no matter if the ORF134 gene was missing or present.
The kidney has an important role in the regulation of acid-base homeostasis. Renal ammonium production and excretion are essential for net acid excretion under basal conditions and during metabolic acidosis. Ammonium is secreted into the urine by the collecting duct, a distal nephron segment where ammonium transport is believed to occur by non-ionic NH(3) diffusion coupled to H(+) secretion.
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