Publications by authors named "Sophie Merk-Loretti"
Mol Cytogenet
August 2008
Article Synopsis
- Malignant melanomas typically show complex genetic changes, but a specific melanoma metastasis to the peritoneal cavity was found to have a stable abnormal karyotype.
- Despite having this unusual stability, the tumor did not exhibit telomerase activity and had relatively short telomeres.
- The findings imply that specific genomic imbalances were crucial for the cancer's progression, without the usual indicators of genetic instability or telomere elongation mechanisms.
