Undiagnosed, untreated acute promyelocytic leukemia presenting as a suspicious sudden death.

Acute promyelocytic leukemia (APL) is a subtype of acute myelogenous leukemia frequently associated with clotting abnormalities and severe hemorrhagic diathesis. The disease is associated with a high incidence of early fatal hemorrhage. We report the sudden death of a 40-year-old male without significant medical history in which foul play had been initially suspected.

Spondylarthropathy striking prevalence in a 19th-20th century Portuguese collection.

Unlabelled: The concept of spondylarthropathy (SPAP) covers a series of pathologies sharing a common genetic basis and infectious triggers.

Objectives: To present and discuss the prevalence of SPAP in the Coimbra identified skeletal collection, a 19th-20th century Portuguese sample.

Materials And Methods: Each of the 505 individuals was macroscopically examined; each joint being assessed for degenerative, inflammatory, ankylosing, entesopathic, traumatic, congenital, infectious, or associated lesions.