Publications by authors named "Sophie Lloret"

Article Synopsis
  • Optimal management of community-acquired intra-abdominal infections (IAI) involves quick surgical intervention and proper antibiotic treatment, with a focus on how timing affects patient outcomes.
  • Conducted across 13 teaching hospitals in France with 205 adult patients, the study measured factors like hospital stay length and mortality rates related to treatment timings.
  • Key findings indicated that delays in surgical source control, higher severity scores, and older age significantly influenced both longer hospital stays and increased risk of 28-day mortality.
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Low peak plasma concentrations (Cmax) of amikacin and gentamicin are reported in intensive care unit (ICU) patients after administration of the first dose. The present study aimed to describe the proportion of ICU patients in whom an adequate Cmax was achieved throughout the course of therapy. Septic ICU patients with an indication for intravenous amikacin or gentamicin were eligible for inclusion in this single-centre observational study.

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