Publications by authors named "Sophie Lefour"
Background: Despite recent progress in the multidisciplinary management of large middle cerebral artery infarcts, the neurological prognosis remains worrying in a non-negligible number of cases. The objective of this study is to analyze the contribution of optic nerve and perioptic sheath measurement on MRI to the acute phase of large middle cerebral artery infarcts.
Methods: A retrospective case-control study between January 2008 and December 2019 in a single academic medical center was performed.
Article Synopsis
- This study explores how different supervised learning algorithms can improve the diagnosis of polyneuropathies, which are often misdiagnosed due to misunderstandings of electrophysiological data.
- The research involved 434 subjects with various types of polyneuropathies, using a majority of the data to train the algorithms and a smaller subset to test their accuracy.
- Results show that the support vector machine (SVM) outperformed both expert and trainee neurophysiologists in diagnosing these conditions, indicating that SVM could be a valuable tool for less experienced doctors.
Background: Hereditary neuropathy with liability to pressure palsies (HNPP) is a rare neuropathy with a heterogeneous clinical profile. Painless recurrent palsies are the usual presentation, but neuropathic pain could be predominant or inaugural. Browsing the medical literature, we only found two articles reffering to this important clinical feature.
View Article and Find Full Text PDFEarly Management of Transient Ischemic Attack in Emergency Departments in France.
J Stroke Cerebrovasc Dis
January 2020
Introduction: Emergency departments play a key role in the diagnosis and treatment of transient ischemic attacks, but limited data are available about the early management of such patients in emergency wards. Therefore, we aimed to evaluate emergency physicians' management of transient ischemic attack and analyze variations factors.
Methods: A multicenter survey among emergency physicians of the Grand Est region network (Est-RESCUE) was conducted from January 28th to March 28th, 2019.
The differential diagnosis between meningioma and others tumors can be challenging. This study aimed to evaluate different immunohistochemical markers for the differential diagnosis between meningioma and their morphological mimics. Immunohistochemistry was performed on tissue microarray with antiepithelial membrane antigen (EMA), progesterone receptor, somatostatin receptor 2A (SSTR2A), CD34, STAT6, S100, SOX10, HMB45, MelanA, GFAP, inhibin, and BCL2 antibodies.
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