Publications by authors named "Sophie L Brigstocke"
Article Synopsis
- Wiskott-Aldrich syndrome (WAS) and X-linked thrombocytopenia (XLT) patients experience microthrombocytopenia, leading to significant bleeding issues.
- Eltrombopag, a thrombopoietic agent, was tested on 9 WAS/XLT patients, resulting in increased platelet counts for 5 out of 8 patients, although platelet activation did not improve significantly.
- The study concluded that while eltrombopag can boost platelet production in WAS/XLT patients, its effect on platelet activation remains limited, particularly when compared to patients with chronic immune thrombocytopenia (ITP).
