Publications by authors named "Sophie Kozelko"
Article Synopsis
- Triple-negative breast cancer (TNBC) is more aggressive than other breast cancer types and lacks targetable biomarkers, making treatment difficult.
- High levels of the sortilin receptor (SORT1) in TNBC patients are associated with decreased survival, especially in those with lymph node metastases.
- A new treatment strategy using a SORT1-targeting peptide (TH19P01) linked to docetaxel (TH1902) has shown increased efficacy in killing TNBC cells and reducing tumor size in mouse models, suggesting it could improve personalized therapy for this cancer subtype.
