Neuropsychological and Neuropsychiatric Concerns for Deep Brain Stimulation in Dystonia: Preoperative Profiles in a Deep Brain Stimulation Cohort and Postoperative Changes in Three Case Series Reports.

Cognitive deficits and psychiatric morbidities are commonly detected in dystonia. Psychiatric disturbances are of particular clinical concern as they not only contribute to poor quality of life and disease associated burden, but also exacerbate motor and cognitive symptoms. Bilateral deep brain stimulation of the globus pallidus internus improves motor symptoms in treatment-resistant dystonia, but its implications for non-motor manifestations are poorly understood.