Akrivia Health Database-deep patient characterisation using a secondary mental healthcare dataset in England and Wales: cohort profile.

Purpose: The Akrivia Health cohort was created to extract data from electronic health records in secondary mental health and dementia care services in England and Wales. The data are anonymised, structured and harmonised from the source electronic health records across a range of information technology systems, enabling for unified, privacy-preserving access for research purposes.

Participants: The cohort contains data from electronic health records for over 4.

Direct and indirect links between children's socio-economic status and education: pathways via mental health, attitude, and cognition.

Unlabelled: A child's socio-economic environment can profoundly affect their development. While existing literature focusses on simplified metrics and pair-wise relations between few variables, we aimed to capture complex interrelationships between several relevant domains using a broad assessment of 519 children aged 7-9 years. Our analyses comprised three multivariate techniques that complimented each other, and worked at different levels of granularity.

Local and global reward learning in the lateral frontal cortex show differential development during human adolescence.

Reward-guided choice is fundamental for adaptive behaviour and depends on several component processes supported by prefrontal cortex. Here, across three studies, we show that two such component processes, linking reward to specific choices and estimating the global reward state, develop during human adolescence and are linked to the lateral portions of the prefrontal cortex. These processes reflect the assignment of rewards contingently to local choices, or noncontingently, to choices that make up the global reward history.

Are the facial gender and facial age variants of the composite face illusion products of a common mechanism?

When the upper half of one face ('target region') is spatially aligned with the lower half of another ('distractor region'), the two halves appear to fuse together perceptually, changing observers' subjective perception of the target region. This 'composite face illusion' is regarded as a key hallmark of holistic face processing. Importantly, distractor regions bias observers' subjective perception of target regions in systematic, predictable ways.