Publications by authors named "Sophie Emond"
Background: There is a paucity of evidence with regard to the safety of contrast medium administration at MRI in neonates and infants.
Purpose: To assess immediate adverse reactions in children younger than 18 months of age during routine clinical utilization of gadoteric acid (Gd-DOTA) in a cohort of patients with nonselected indications.
Materials And Methods: One hundred and four neonates and infants were enrolled in a postmarketing survey with Gd-DOTA (Dotarem, Guerbet, Roissy, France) from a single pediatric hospital.
Objectives: To describe the long-term course and the management in children of chronic interstitial lung disease associated with I73T mutation.
Materials And Methods: Clinical, radiological, and histological data from one family including five children and two adults were analyzed retrospectively for three patients and prospectively for the others.
Results: Mean age of onset of respiratory symptoms for children was 6 months (2-15 months).
A child was referred for evaluation after prenatal diagnosis with macrosomia, clitoromegaly, labial hypertrophy, and a left ovarian cyst. The karyotype was 46,XX. The postnatal pelvic ultrasound was normal.
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- The study aimed to assess how accurately CT scans can diagnose chronic infiltrative lung diseases in children by evaluating data from 59 patients over 14 years.
- Out of the CT observations, the correct first-choice diagnosis occurred 38% of the time, with pulmonary alveolar proteinosis being the most accurately identified condition.
- Results highlight the limitations of relying solely on CT scans for these diagnoses, suggesting issues like technical challenges in imaging children and the variability of lung disease presentations contribute to the lower accuracy rates.
Chest computed tomography findings in bronchopulmonary dysplasia and correlation with lung function.
Arch Dis Child Fetal Neonatal Ed
November 2007
Objective: With changes in the predominant pathogenic factors in the new form of bronchopulmonary dysplasia (BPD), a different pattern of CT findings may be expected. This study aimed to (1) describe CT findings in infants with BPD and (2) correlate the CT findings with lung function abnormalities.
Study Design And Method: Retrospective review of 41 very low birthweight infants with BPD, who were referred for pulmonary investigations at between 10 and 20 months after birth because of persistent respiratory symptoms, and underwent CT and lung function tests.
Background: There are numerous causes of bilateral hyperechoic kidneys. Congenital disorders of glycosylation (CDGs) are a rapidly growing family of inherited disorders due to defects in the synthesis of the glycans of glycoproteins or other glycoconjugates.
Objective: To describe renal sonographic abnormalities in CDG type I in infants and children.
Background: Children with severe asthma have a significantly higher bronchial wall thickness (BWT) on high-resolution computed tomography scan than control children.
Objective: We sought to determine whether a BWT score correlates with markers of airway remodeling and inflammation.
Methods: In 37 children with severe asthma, we determined reticular basement membrane thickness; number of intraepithelial neutrophils and eosinophils on bronchial biopsy; IFN-gamma, IL-4, IL-5, and eosinophil cationic protein levels and IFN-gamma/IL-4 ratio on bronchoalveolar lavage specimen; and alveolar nitric oxide (NO) concentration and the maximum airway wall NO flux.
We report a case of GM2 gangliosidosis revealed by MR imaging of an isolated brain stem abnormality in a 3-year-old girl referred for gait difficulties related to ataxia and pyramidal signs. Brain MR imaging displayed a brain stem lesion with high signal intensity on fluid-attenuated inversion recovery and T2-weighted images, suggesting either a tumor or an inflammatory process. Stereotactic biopsy findings showed the presence of swollen neurons with storage material in lysosomes.
View Article and Find Full Text PDFBackground/purpose: Although much is known about the prenatal course of cystic adenomatoid malformations (CCAM), the postnatal course of asymptomatic lesion is less well documented. The authors studied the pre- and postnatal course and treatment of asymptomatic CCAM.
Methods: The authors reviewed the files of all patients referred to Necker-Enfants Malades hospital with an antenatal diagnosis of CCAM and asymptomatic at birth.
Objective: . The aim of this study was to establish objective, simple criteria for bronchial wall thickening in children with difficult-to-treat asthma.
Subjects And Methods: .